Modeling yield properties of compacted powder using a multi-particle finite element model with cohesive contacts

Loidolt, Peter; Ulz, Manfred Hannes; Khinast, Johannes G.

doi:10.1016/j.powtec.2018.06.018

Cited by 27 publications

(9 citation statements)

References 48 publications

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“…The compaction of deformable matter has been addressed in experiments using ceramic, metallic, and pharmaceutical powders [1][2][3][4][5], gels [6][7][8], rubberlike particles [9][10][11][12], and even blood cells [13]. More recently, developments of numerical approaches based on meshless methods [14][15][16], the discrete element method [17,18], or the coupled finite element-discrete element methods [11,[19][20][21][22][23][24] have enabled the exploration of the physics of deformable granular media.…”

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confidence: 99%

Compaction Model for Highly Deformable Particle Assemblies

et al. 2020

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The compaction behavior of deformable grain assemblies beyond jamming remains bewildering, and existing models that seek to find the relationship between the confining pressure P and solid fraction ϕ end up settling for empirical strategies or fitting parameters. Using a coupled discrete-finite element method, we analyze assemblies of highly deformable frictional grains under compression. We show that the solid fraction evolves nonlinearly from the jamming point and asymptotically tends to unity. Based on the micromechanical definition of the granular stress tensor, we develop a theoretical model, free from ad hoc parameters, correctly mapping the evolution of ϕ with P. Our approach unveils the fundamental features of the compaction process arising from the joint evolution of grain connectivity and the behavior of single representative grains. This theoretical framework also allows us to deduce a bulk modulus equation showing an excellent agreement with our numerical data.

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confidence: 99%

Compaction Model for Highly Deformable Particle Assemblies

et al. 2020

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“…The microstructure is usually modelled using a Representative Volume Element (RVE) with periodic boundary conditions (PBCs) so that infinitely large periodic systems can be simulated. Computational homogenization techniques are used to determine the material behaviour on the macroscale [27,28].…”

Section: Mesoscopic Approach To Powder Compactionmentioning

confidence: 99%

A Multiscale Material Model for Metallic Powder Compaction During Hot Isostatic Pressing

Elguezabal¹,

Alkorta²,

Martinez-Esnaola³

et al. 2023

Preprint

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“…A recent specialized FEM technique used to examine the strength and damage of compacted powder was conducted by Loidolt et al [ 177 ] in which the multi-particle finite element method (MPFEM) popularized by Gethin et al [ 144 ] and Procopio et al [ 145 ] was updated to include cohesive contact between FEM particle boundaries. In addition, a novel way of incorporating periodic boundary conditions was introduced, which allowed for the generation of an efficient representative volume element (RVE) for compaction of powder and the description of yield surfaces as a function of different cohesive particle-particle contact strengths.…”

Section: Modeling Of Batch Processesmentioning

confidence: 99%

Direct Compaction Drug Product Process Modeling

et al. 2022

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Most challenges during the development of solid dosage forms are related to the impact of any variations in raw material properties, batch size, or equipment scales on the product quality and the control of the manufacturing process. With the ever pertinent restrictions on time and resource availability versus heightened expectations to develop, optimize, and troubleshoot manufacturing processes, targeted and robust science-based process modeling platforms are essential. This review focuses on the modeling of unit operations and practices involved in batch manufacturing of solid dosage forms by direct compaction. An effort is made to highlight the key advances in the past five years, and to propose potentially beneficial future study directions.

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Modeling yield properties of compacted powder using a multi-particle finite element model with cohesive contacts

Cited by 27 publications

References 48 publications

Compaction Model for Highly Deformable Particle Assemblies

Compaction Model for Highly Deformable Particle Assemblies

A Multiscale Material Model for Metallic Powder Compaction During Hot Isostatic Pressing

Direct Compaction Drug Product Process Modeling

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