This article describes the multi-response optimization of electrochemical machining operating parameters such as voltage, concentration of the electrolyte, and current to maximize the rate of material removal in addition to minimize the over cut and delamination at the same time in micro-drilling of AA6061-TiB2 in situ composite. A novel Entropy–VIKOR method is applied to handle such mutually conflicting responses. The weight of each response is computed from the entropy method, and VIKOR method is used to rank the various levels of parameters. This method yields the combination of 2 mol of electrolyte concentration, 16 V of applied voltage, and 4 A of current as optimal parameters to minimize the over cut and delamination in addition to maximize the rate of material removal at the same time. This optimal process-governing parameters satisfied the conditions for compromising solution such as acceptable advantage and acceptable stability condition. The response graph illustrates that, of the parameters investigated, electrolyte concentration has the greatest effect on the VIKOR index, followed by applied voltage and current. Scanning electron microscopic analysis illustrates that the radius of the hole is equal throughout the periphery, except for one instance of micro-delamination.