Modelling Bovine Tuberculosis in Badgers

Bentil, Daniel E.; Murray, J. D.

doi:10.2307/5355

Cited by 31 publications

(29 citation statements)

References 18 publications

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“…In early SEI models [4,15], badgers were considered to become infectious upon detection of M. bovis bacilli excreted from lesions. Estimates of disease-induced mortality in infectious badgers ranged from 0 % [15] to 100 % [4].…”

Section: Introductionmentioning

confidence: 99%

Multi-state modelling reveals sex-dependent transmission, progression and severity of tuberculosis in wild badgers

et al. 2013

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Statistical models of epidemiology in wildlife populations usually consider diseased individuals as a single class, despite knowledge that infections progress through states of severity. Bovine tuberculosis (bTB) is a serious zoonotic disease threatening the UK livestock industry, but we have limited understanding of key epidemiological processes in its wildlife reservoirs. We estimated differential survival, force of infection and progression in disease states in a population of Eurasian badgers (Meles meles), naturally infected with bTB. Our state-dependent models overturn prevailing categorizations of badger disease states, and find novel evidence for early onset of disease-induced mortality in male but not female badgers. Males also have higher risk of infection and more rapid disease progression which, coupled with state-dependent increases in mortality, could promote sex biases in the risk of transmission to cattle. Our results reveal hidden complexities in wildlife disease epidemiology, with implications for the management of TB and other zoonotic diseases.

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Section: Introductionmentioning

confidence: 99%

Multi-state modelling reveals sex-dependent transmission, progression and severity of tuberculosis in wild badgers

et al. 2013

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“…Badgers are social animals and usually live in groups with de®ned territories (Kruuk, 1978;Cheeseman, Jones et al, 1981). Numerous models have now been created to simulate the epidemiology/disease dynamics of M. bovis in badgers (Anderson & Trewhella, 1985;Bentil & Murray, 1993;Smith, Richards et al, 1995;White & Harris, 1995;Ruxton, 1996;Smith, Cheeseman & Clifton-Hadley, 1997;Swinton et al, 1997). Moreover, four TB health states have been recognized which includes a state of intermittent bacterial excretion (Smith, Richards et al, 1995).…”

Section: Introductionmentioning

confidence: 99%

The effects of bovine tuberculosis (Mycobacterium bovis) on mortality in a badger (Meles meles) population in England

Wilkinson¹,

Smith²,

Delahay³

et al. 2000

Journal of Zoology

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The mortality rates of badgers Meles meles were estimated, using data from a long-term capture±mark± recapture study of an undisturbed badger population in south-west England. Two life table methods were used: fusion and discounting. Badgers were allocated to a particular TB status for all or part of their lives according to their degree of infection with bovine tuberculosis Mycobacterium bovis. Separate life tables were created for animals with each TB status, and for males and females, and the estimated mortality rates were compared statistically. The progression of M. bovis infection, and the positions of M. bovis lesions were also analysed. The main ®ndings are: (a) uninfected male badgers have a signi®cantly higher mortality rate than uninfected females, (b) infected badgers which are not excreting M. bovis do not have a signi®cantly higher mortality rate than uninfected badgers, (c) badgers which are excreting M. bovis have a much higher mortality rate than uninfected badgers, (d) male badgers appear to cope with M. bovis infection less well than females, and (e) there may be sex differences in the mode of spread of M. bovis in badgers.

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“…Similar deterministic models have been developed for the dynamics of M. bovis infection in badger populations (e.g. Anderson andTrewhella, 1985;Bentil and Murray, 1993;White and Harris, 1995), though the modelling results from these and numerous other studies are not formally incorporated into current badger control strategies. This study monitored annual changes in possum abundance, the prevalence of macroscopic M. bovis infection in possums and the incidence ofTb in cattle resulting from 10 years of possum maintenance control at a site in the Central North Island.…”

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confidence: 96%

Effects of sustained control of brushtail possums on levels ofMycobacteriumbovis infection in cattle and brushtail possum populations from Hohotaka, New Zealand

Caley¹,

Hickling²,

Cowan³

et al. 1999

New Zealand Veterinary Journal

102

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The results support the hypothesis that tuberculous possums transmit bovine tuberculosis to domestic cattle, and therefore that reducing the abundance of tuberculous possums reduces the incidence of Tb in cattle. If the level of possum culling is sufficient, it appears that M. bovis infection may be eradicated from possum populations. Better information on population density, rate of increase and annual culling rates would have been needed for a truly independent examination of the Barlow possum-Tb model.

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Modelling Bovine Tuberculosis in Badgers

Cited by 31 publications

References 18 publications

Multi-state modelling reveals sex-dependent transmission, progression and severity of tuberculosis in wild badgers

Multi-state modelling reveals sex-dependent transmission, progression and severity of tuberculosis in wild badgers

The effects of bovine tuberculosis (Mycobacterium bovis) on mortality in a badger (Meles meles) population in England

Effects of sustained control of brushtail possums on levels ofMycobacteriumbovis infection in cattle and brushtail possum populations from Hohotaka, New Zealand

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