To systematically review published literature for the research question 'what issues are considered (and changes made) for vulnerable groups as part of the Chemical. Biological, Radiological, Nuclear or explosive (CBRNe) response for casualty collection, decontamination, triage and casualty clearing processes?' Design: Seven-stage framework from the PRISMA statement for research question, eligibility (definition), search, identification of relevant papers from title and abstract, selection and retrieval of papers, appraisal and synthesis.