2014
DOI: 10.1364/boe.5.002285
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Modelling of diffraction grating based optical filters for fluorescence detection of biomolecules

Abstract: Abstract:The detection of biomolecules based on fluorescence measurements is a powerful diagnostic tool for the acquisition of genetic, proteomic and cellular information. One key performance limiting factor remains the integrated optical filter, which is designed to reject strong excitation light while transmitting weak emission (fluorescent) light to the photodetector. Conventional filters have several disadvantages. For instance absorbing filters, like those made from amorphous silicon carbide, exhibit low … Show more

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Cited by 2 publications
(1 citation statement)
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“…In another work, FEM was used for modelling diffraction grating based optical filters for fluorescence detection of biomolecules. Authors have evaluated three filter concepts using the FEM modelling [106], namely placement of the diffraction grating, embedded diffraction grating in a low refractive index medium and combination with a flat absorbing filter. The first one showed minimal improvements in terms of filter efficiency, while the other to produces high efficiencies (in the order of 10 5 ).…”
Section: Optical Filtersmentioning
confidence: 99%
“…In another work, FEM was used for modelling diffraction grating based optical filters for fluorescence detection of biomolecules. Authors have evaluated three filter concepts using the FEM modelling [106], namely placement of the diffraction grating, embedded diffraction grating in a low refractive index medium and combination with a flat absorbing filter. The first one showed minimal improvements in terms of filter efficiency, while the other to produces high efficiencies (in the order of 10 5 ).…”
Section: Optical Filtersmentioning
confidence: 99%