“…Trickle-bed reactors are employed in petroleum, petrochemical and chemical industries, in waste treatment and in biochemical and electrochemical processing as well as other application [5] Various flow regimes exist in TBRs depending on the superficial mass velocity, fluid properties and bed characteristics [6,7] such as trickle flow, pulsing flow, mist flow and bubble flow [7]. The performance of a trickle-bed reactor is affected, not only by reaction kinetics, pressure, and temperature, but also by reactor hydrodynamics, which are commonly described by means of global parameters such as pressure drop, liquid holdup, dispersion of gas and liquid phases, catalyst wetting, and mass-and heat-transfer coefficients [8]. Liquid holdup and pressure drop in the bed are the two key hydrodynamic parameters whose knowledge is necessary while designing and scaling up of the reactor [9].…”