Modelling the Effect of the Exposure to Perfluorooctanoate (PFOA) and Perfluorooctane Sulfonate (PFOS) on Thyroid Homeostasis
Chontita Rattanakul
Abstract:Thyroid homeostasis is crucial for the human body. The imbalance of thyroid homeostasis might cause diseases such as hypothyroidism. Humans are exposed to PFOS/PFOA frequently since they have been used in various industrial products. As reported that PFOS/PFOA increase the metabolic clearance rate of thyroid hormones, we then develop a mathematical model in terms of a system of differential equations to investigate thyroid homeostasis based on the changes in the levels of thyrotropin-releasing hormone, thyroid… Show more
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