Modelling the impact of some control strategies on the transmission dynamics of Ebola virus in human-bat population: An optimal control analysis

Agbomola, Joshua Oluwasegun; Loyinmi, Adedapo Chris

doi:10.1016/j.heliyon.2022.e12121

Cited by 6 publications

(6 citation statements)

References 42 publications

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“…Any further responses from the reviewers can be found at the end of the article Researchers have employed numerous tools to manage and eradicate HIV/AIDS diseases. 3,11,12 In order to study the combined effects of three control measures, 49 presented an innovative and workable human-bat (host-vector) model that predicts the spread and severity of the Ebola virus from bats to humans. To demonstrate the model's epidemiological viability, among other things, disease-free equilibrium, the endemic equilibrium, local and global stability, positivity, and boundedness were established.…”

Section: Revised Amendments From Versionmentioning

confidence: 99%

Qualitative analysis of HIV and AIDS disease transmission: impact of awareness, testing and effective follow up

Abiodun

Adebimpe²,

Ndako³

et al. 2023

F1000Res

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Background: Since the early 1980s, human immunodeficiency virus (HIV) and its accompanying acquired immunodeficiency syndrome (AIDS) have spread worldwide, becoming one of the world's major global health issues. From the beginning of the epidemic until 2020, about 79.3 million people became infected, with 36.3 million deaths due to AIDS illnesses. This huge figure is a result of those unaware of their status due to stigmatization and invariably spreading the virus unknowingly. Methods: Qualitative analysis through a mathematical model that will address HIV unaware individuals and the effect of an increasing defaulter on the dynamics of HIV/AIDS was investigated. The impact of treatment and the effect of inefficient follow-up on the transmission of HIV/AIDS were examined. The threshold for the effective reduction of the unaware status of HIV through testing, in response to awareness, and the significance of effective non-defaulting in treatment commonly called defaulters loss to follow-up as these individuals contribute immensely to the spread of the virus due to their increase in CD4+ count was determined in this study. Stability analysis of equilibrium points is performed using the basic reproduction number $R_0$, an epidemiological threshold that determines disease eradication or persistence in viral populations. We tested the most sensitive parameters in the basic reproduction numbers. Results: The results portray that early identification and treatment only are inadequate for the illness to be eradicated, but effectively used of condom, strict adherence to treatment and counseling of and testing of pregnant women contribute to a decrease in infected HIV individuals. Conclusions: Other control techniques, such as treatment adherence and effective condom usage, and reduction in vertical transmission cannot be over-emphasis to lessen the disease's burden. Policymakers must address these strategies through a series of public awareness campaigns about the dangers of not adhering to treatment procedures and patterns.

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Section: Revised Amendments From Versionmentioning

confidence: 99%

Qualitative analysis of HIV and AIDS disease transmission: impact of awareness, testing and effective follow up

Abiodun

Adebimpe²,

Ndako³

et al. 2023

F1000Res

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show abstract

“…Studying and learning from the successful strategies used during these outbreaks could prove valuable in preparing for future outbreaks and improving our ability to contain them. By adopting a similar multilevel and multisectoral approach, we may be able to generate a more effective response and reduce the impact of future Ebola outbreaks [ 52 ]. Public education about this deadly disease is also critical for preventing its spread [ 53 ].…”

Section: Prevention and Controlmentioning

confidence: 99%

Brief review on ebola virus disease and one health approach

Hussein

2023

Heliyon

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“…Due to the rapid rate of spread of corona virus in Nigeria, It is important to formulate a model to examine the disease flow and dissemination, including quarantined persons, hospitalized/confirmed patients, and pathogen concentrations in the environment. However, presently, COVID-19 has no cure and it is very dangerous to human health (Elengoe, 2020;Agbomola and Loyinmi, 2022;Akinfe and Loyinmi, 2021). COVID-19 has caused 3,142 deaths across the country as of March 21, 2022(NCDC, 2022.…”

Section: Figure 1 Diagram Showing the Shape Of Covid-19mentioning

confidence: 99%

Qualitative Analysis of the Transmission Dynamics and Optimal Control of Covid-19

Idowu

Loyinmi

2023

Preprint

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Globally, the COVID-19 presents a serious concern to the wellbeing of people. COVID-19 was first detected in Wuhan, China. The disease became a source of concern for Nigerians after the country registered its first case in February 2020. Currently, the country has recorded 255,103 confirmed cases, 249,246 recovered cases, and 3,142 deaths as of March 21, 2022. We proposed a SEQIHRV model to investigate the spread of coronavirus disease in Nigeria. This model defines the infection dynamics' transmission routes as well as effect of contaminated surfaces on the human population. Unfortunately, the virus's propagation and mortality from COVID-19 is increasing daily. Therefore, it is required to manage and control the flow of the infection. The impact of control measures as time-dependent interventions was investigated in this study utilizing optimization technique to determine their effects on the spread of Corona virus. The basic reproduction was calculated and used to calcite the sensitive parameters affecting the system, which revealed the key parameters leading to COVID-19 propagation. The control optimization of the sytem was performed using Pontryagin's maximum principle to determine the best approach for controlling the spread. The discoveries from the simulation showed that the combination of all four control approaches will help to reduce infection to zero in the population.

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Modelling the impact of some control strategies on the transmission dynamics of Ebola virus in human-bat population: An optimal control analysis

Cited by 6 publications

References 42 publications

Qualitative analysis of HIV and AIDS disease transmission: impact of awareness, testing and effective follow up

Qualitative analysis of HIV and AIDS disease transmission: impact of awareness, testing and effective follow up

Brief review on ebola virus disease and one health approach

Qualitative Analysis of the Transmission Dynamics and Optimal Control of Covid-19

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