2022
DOI: 10.1101/2022.06.08.495414
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Modelling the metabolic consequences of antimicrobial exposure

Abstract: Besides genetic mutations, the metabolic state of bacterial cells represents another driving factor in the emergence of antimicrobial resistance and in the actual efficacy of treatments. In this direction, studying how bacteria reprogram their metabolism when facing antimicrobial exposure is crucial to enhance our ability to limit the development and spread of antibiotic resistance. Here we have studied the metabolic consequences of antimicrobial exposure in bacteria using an integrated approach that exploits … Show more

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