Moderate Alcohol Use and Reduced Mortality Risk: Systematic Error in Prospective Studies and New Hypotheses

Fillmore, Kaye Middleton; Stockwell, Tim; Chikritzhs, Tanya; Bostrom, Alan; Kerr, William C.

doi:10.1016/j.annepidem.2007.01.005

Cited by 324 publications

(264 citation statements)

References 58 publications

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“…al. argue that the cardiac protection afforded by alcohol may have been over-estimated [11]. An association between breast cancer and alcohol use has been shown in other studies.…”

Section: Discussionmentioning

confidence: 93%

“…"sick quitters". In some studies the "protective effect" of alcohol use may be explained by the fact that former drinkers have been included among non-drinkers [11,20]. However, others have observed J-or U-shaped associations even after separating former drinkers from life-long abstainers [21][22].…”

Section: Discussionmentioning

confidence: 99%

“…On the other hand, older individuals run considerable risks associated with alcohol use due to pre-existing health conditions, heavier use of prescribed medications, greater risk of balance problems, and/or cognitive dysfunction compared to younger people [10]. Furthermore, in a large meta-analysis Fillmore et al concluded that the cardiac protection afforded by alcohol may be over-estimated [11].…”

Section: Introductionmentioning

confidence: 99%

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Alcohol use and early mortality in Swedish middle-aged women: Nine-year follow-up of the Women’s Health in Lund Area study

Rundberg

Nilsson

Samsioe

et al. 2014

Scand J Public Health

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Aims: The majority of prospective studies on alcohol use and mortality risk indicate that nondrinkers are at increased risk of death compared to moderate drinkers. This paper investigates the association between middle-aged women's alcohol use and mortality, controlling for socio-demographic and health variables. An association between alcohol use and hospital inpatient care is also analysed.Methods: Baseline data were collected 1995-2000 in a population-based cohort of 6917 women aged 50-59 years living in southern Sweden, the Women's Health in Lund Area (WHILA). After nine years a register follow-up was performed from the National cause-ofdeath register and the Swedish hospital discharge register. Cox proportional hazards regression were used to analyse differences in survival.Results: During the observation period 201 (2.9%) women died. In a crude model nondrinkers had a significantly increased risk for death. When including socio-demographic predictors in the model there was a strong indication that non-drinkers were at increased risk for death compared to moderate drinkers. Adding health predictors, not drinking alcohol was no longer a risk factor for death. Further, analyses of in-patient care indicate that non-drinkers had poorer health during their entire adult life.Conclusions: This study underlines the importance of including health status at base-line when prospectively studying the association between alcohol use and mortality, otherwise moderate alcohol consumption may appear more beneficial than is the case.

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“…al. argue that the cardiac protection afforded by alcohol may have been over-estimated [11]. An association between breast cancer and alcohol use has been shown in other studies.…”

Section: Discussionmentioning

confidence: 93%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Alcohol use and early mortality in Swedish middle-aged women: Nine-year follow-up of the Women’s Health in Lund Area study

Rundberg

Nilsson

Samsioe

et al. 2014

Scand J Public Health

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show abstract

“…O consumo moderado de álcool pode ter um impacto psicológico positivo, com alívio do sofrimento emocional e ser eficaz para lidar com situações sociais e de ansiedade 32 . É importante enfatizar que as pessoas que envelhecem apresentam maior prevalência de doenças e consomem mais medicamentos o que tende a diminuir ou cessar a ingestão do consumo de álcool 33,34 , mas no presente estudo, mesmo ajustado para número de morbidades referidas os transtornos mentais comuns, mostraram-se menos prevalentes nos idosos que consomem bebidas alcoólicas. Outros estudos de corte transversal observaram maior prevalência de ativos no lazer 35 , melhor qualidade de vida 36 e melhor autoavaliação de saúde 37 nos idosos que consumiam bebidas alcoólicas moderadamente.…”

Section: Discussionunclassified

Transtorno mental comum na população idosa: pesquisa de base populacional no Município de Campinas, São Paulo, Brasil

Borim¹,

Barros²,

Botega³

2013

Cad. Saúde Pública

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“…Este proceder tiende a sobreestimar el efecto protector de los bajos niveles de consumo y a subestimar el efecto negativo de los niveles altos debido a que entre los abstemios hay antiguos bebedores que han dejado el alcohol por presentar problemas relacionados con esta sustancia. En consecuencia, tienen riesgo más alto de muerte por todas las causas y por coronariopatía y peor salud percibida que quienes han sido abstemios toda la vida o lo han sido de larga duración [4][5][6][7][8][9] .…”

Section: Métodos Para Estudiar La Relación Entre Consumo De Alcohol Yunclassified

Métodos de investigación sobre daños en la población relacionados con el alcohol

Ruiz¹,

Sordo

Pulido

et al. 2014

Rev. Esp. Salud Publica

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Moderate Alcohol Use and Reduced Mortality Risk: Systematic Error in Prospective Studies and New Hypotheses

Cited by 324 publications

References 58 publications

Alcohol use and early mortality in Swedish middle-aged women: Nine-year follow-up of the Women’s Health in Lund Area study

Alcohol use and early mortality in Swedish middle-aged women: Nine-year follow-up of the Women’s Health in Lund Area study

Transtorno mental comum na população idosa: pesquisa de base populacional no Município de Campinas, São Paulo, Brasil

Métodos de investigación sobre daños en la población relacionados con el alcohol

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