Moderate intake of sucrose does not impair metabolic control in pump-treated diabetic out-patients

Chantelau, Ernst; Gösseringer, G.; Sonnenberg, G. E.; Berger, Michael

doi:10.1007/bf00282233

Cited by 72 publications

(45 citation statements)

References 14 publications

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“…Our results support recent findings in adults [3,7,11,14,19], children [15] and teenagers [6] with diabetes, where sucrose as part of mixed meals or larger snacks had no negative effect on the postprandial blood glucose response. The findings of Shiverly et al [18] that a potato chips snack in healthy subjects resulted in a lower blood glucose AUC than to other common snacks, was supported by our study.…”

Section: Discussionsupporting

confidence: 95%

Glycaemic effect and satiating capacity of potato chips and milk chocolate bar as snacks in teenagers with diabetes

1993

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In 14 adolescents with diabetes, the postprandial blood glucose, after ingestion of two popular snacks, milk chocolate bar and potato chips, was compared to a prescribed mid-afternoon snack that was isocaloric with the comparison snacks. The prescribed diabetes snack consisted of wholemeal wheat bread, margarine, cheese and apple (1533 kJ/365 kcal): 14% protein, 32% fat and 54% carbohydrate. The milk chocolate bar and the potato chips contained 4% protein, 55% fat and 41% carbohydrate. The mean blood glucose peak was 4.7 (+/- 0.8) mmol/l after the regular diabetes snack, after the milk chocolate bar 2.9 (+/- 0.6) mmol/l, and 3.2 (+/- 0.6) mmol/l after the potato chips (P > 0.05). The mean incremental area under the blood glucose curve was 450.3 (+/- 105.5) mmol/l x 180 min for the regular diabetes snack, 269.5 (+/- 96.7) mmol/l x 180 min for the milk chocolate bar and 191.7 (+/- 95.0) mmol/l x 180 min for the potato chips (P > 0.05). We conclude that an occasional exchange of a regular diabetes afternoon snack for an isocaloric amount of milk chocolate bar or potato chips has no negative impact on the postprandial blood glucose.

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Section: Discussionsupporting

confidence: 95%

Glycaemic effect and satiating capacity of potato chips and milk chocolate bar as snacks in teenagers with diabetes

1993

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“…In contrast with these studies, there are five reports that suggest that increased dietary sucrose consumption over a period of 8 days to 6 wk did not result in adverse metabolic effects (21)(22)(23)(24)(25). In one of these studies the authors reported no significant metabolic effects of replacing 45 g of complex carbohydrate with an equal amount of sucrose (21).…”

Section: Cb Hollenbeck Am Coulston and Gm Reaven Clinical Stumentioning

confidence: 58%

“…In a second outpatient study, Chantelau et al (22) reported no significant differences in the degree of blood glucose control or plasma lipid concentrations after diets containing either sucrose or sodium cyclamate in 10 patients with IDDM receiving continuous subcutaneous insulin-infusion therapy. However, the level of dietary sucrose reportedly consumed in their study was only 24…”

Section: Cb Hollenbeck Am Coulston and Gm Reaven Clinical Stumentioning

confidence: 99%

Effects of Sucrose on Carbohydrate and Lipid Metabolism in NIDDM Patients

1989

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Recently, there has been increasing interest toward the liberalization of sucrose in the diets of individuals with non-insulin-dependent diabetes mellitus (NIDDM).However, there is evidence from several well-controlled prospective studies demonstrating that the consumption of moderate amounts of sucrose may result in hyperglycemia, hyperinsulinemia, hypertriglyceridemia, hypercholesterolemia, and reduced high-density lipoprotein cholesterol concentrations. The fact that not all studies demonstrate these deleterious effects does not negate the positive data. The magnitude of the deleterious effects will probably vary with individual patients, baseline status, and amount of sucrose. Because these metabolic abnormalities are most disturbed in diabetes and are associated with increased risk of coronary artery disease, it would seem reasonable to continue to advise patients with NIDDM to limit sucrose consumption, at least until available data would allow us to predict in which individuals and at what level of sucrose consumption these adverse metabolic effects would not be present. Diabetes Care 12:62-66, 1989 T here is general agreement that diet should serve as the cornerstone of any therapeutic program for the treatment of diabetes. Understanding the impact of variations in diet composition on the metabolic defects present in diabetes, however, is far from clear. This is particularly true in regard to what impact sucrose may have in controlling the abnormalities in carbohydrate and lipid metabolism present in diabetes. As interest in the dietary management of diabetes has intensified, attention has been directed toward the potential role that specific dietary manipulations might have in reducing the increased risk of coronary artery disease (CAD) associated with diabetes. In this regard, the issue of dietary sucrose must assume a prominent role in the discussion of the dietary treatment of diabetes. Recent statements from both the American Diabetes Association (1) and Food and Drug Administration (2) suggest there may be no adverse health effects associated with increased sucrose consumption in patients with diabetes. On the other hand, there is evidence from several wellcontrolled prospective studies suggesting that the consumption of moderate amounts of sucrose may result in a series of deleterious metabolic effects that are associated with an increased risk for the development of CAD (3-10). Specifically, studies have shown that the addition of moderate amounts of sucrose are associated with hyperglycemia, hyperinsulinemia, hypertriglyceridemia, hypercholesterolemia, and reduced high-density lipoprotein cholesterol (HDL-chol) concentrations. These metabolic abnormalities are most disturbed in diabetes (17,18 ,31,32) and are associated with the increased risk of CAD (30-34); therefore, it would seem reasonable to question the general recommendation liberalizing sucrose consumption in these individuals. In this article, we discuss the evidence from our group and others designed to assess the metabolic impact of...

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“…Note that questions have been raised in recent years about whether the avoidance of sucrose really facilitates metabolic control (9)(10)(11)(12)(13)(14). Nevertheless, most clinicians and health professionals, as well as official American Diabetes Association policy (15), recommend some degree of limitation of sucrose in the diet.…”

Section: Pa Crapomentioning

confidence: 99%

Use of Alternative Sweeteners in Diabetic Diet

Crapo

1988

Diabetes Care

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Alternative sweeteners are widely advocated and used. However, there is insufficient scientific information to determine whether alternative sweeteners are of value in the management of diabetes, either in improving dietary adherance or in contributing to the achievement or maintenance of a lower body weight. Each of the available sweeteners has advantages and disadvantages; no one is preferred. Recommendations about alternative-sweetener use should be tailored to the specific dietary and life-style patterns of the individual. Diabetes Care 11:174-82, 1988 S ucrose, glucose, and foods containing large amounts of the two refined sugars have been restricted in various dietary approaches throughout the history of diabetes therapy (1), particularly throughout much of this century, as a means of limiting excursions of blood glucose. (Simple sugars in the form of fruits, vegetables, and dairy products have variably been excluded from this practice.) Consequently, alternative sweeteners, both caloric (fructose, sorbitol, mannitol) and noncaloric (saccharin, aspartame, cyclamate), have played a dominant role in the provision of sweetness in diabetic diets. Despite this, many questions about their use remain. Are alternative sweeteners actually of any value in the management of diabetes? Do they help people with diabetes adhere to their diabetic diets? Do they help in the treatment of the obesity associated with type II (non-insulin-dependent) diabetes? What are the side effects of the different sweet-

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Moderate intake of sucrose does not impair metabolic control in pump-treated diabetic out-patients

Cited by 72 publications

References 14 publications

Glycaemic effect and satiating capacity of potato chips and milk chocolate bar as snacks in teenagers with diabetes

Glycaemic effect and satiating capacity of potato chips and milk chocolate bar as snacks in teenagers with diabetes

Effects of Sucrose on Carbohydrate and Lipid Metabolism in NIDDM Patients

Use of Alternative Sweeteners in Diabetic Diet

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