Background Depression and diabetes mellitus are health problems that affect people's quality of life. Some diabetic patients who are depressed may remain undiagnosed with the co- morbidity by Family Physicians. Hence there is need to draw physicians’ attention to curb this. Aim/Objectives The objective of this study was to assess the prevalence and risk factors of depression among type 2 diabetic patients attending Federal Medical Centre's General Outpatient Clinic in Makurdi, Nigeria Methodology This cross-sectional study included 238 diabetic patients over the age of 18 using the random sampling technique. Self-completed questionnaires were used to collect data, and clinical parameters such as height, weight, blood pressure, and fasting blood glucose levels were noted. The questionnaire collected information on the socio- demographic characteristics, relevant history and Becks Depression Inventory (BDI). Version 21 of the SPSS (Statistical Package for Social Sciences) was used to analyze the data. P-values of less than 0.05 were considered statistically significant in all analyses, which were carried out at a 5% significance level. Results It was shown that 33.6% of people had depression. It was more common in people between the ages of 20 and 29 (50%) and in women than in men (39% vs. 25%). Mild depression was present in 56.3% of diabetic patients with depression. Depression was shown to be significantly correlated with BMI (p = 0.002), marital status (p = 0.034), gender (p = 0.026), and the kind of antidiabetic medicine taken (p = 0.036). Being overweight was substantially linked to a decreased risk of depression, according to multiple logistic regression analysis (aOR = 0.14, CI = 0.03-0.66, p = 0.013). Conclusion/Recommendation A considerable number of diabetic patients exhibited depression. Physicians should maintain a high level of vigilance, monitor the behavior of individuals with diabetes, and screen them for depression. This approach can provide a foundation for further research.