Moderating effects of social support on the relationship between substance use disorders and HIV viral load and medication adherence among Black women living with HIV in the United States

Reid, Rachelle; Dale, Sannisha K.

doi:10.1080/09540121.2021.2001415

Cited by 8 publications

(2 citation statements)

References 48 publications

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“…This finding was supported by Reidand Dale. 22 The result showed that smoker adult HIV infected patients had a higher viral load than non-smoker patients. Also, the predictor substance use was a significant predictor for medication adherence.…”

Section: Discussionmentioning

confidence: 96%

Predictors of Viral Load and Medication Adherence Among HIV-Positive Adults Under Treatment at Felege-Hiwot Comprehensive Specialized Hospital, North-West, Ethiopia

Hussen Tale,

Tegegne,

Belay

2023

HIV

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Background Maintaining good medication adherence and decreasing viral load in patients living with HIV/AIDS are critical to ensuring antiretroviral therapy’s preventive and therapeutic benefits. The main objective of this study was to assess the predictors of viral load and medication adherence among HIV-positive adults under treatment at Felege Hiwot Comprehensive Specialized Hospital (FHCSH). Methods A retrospective cohort study design was conducted from a random sample of 281 adult HIV-infected patients under treatment at FHCSH in northwest Ethiopia from June 2017 to June 2021. Separate GLMM was used in analysis of viral load and medication adherence, and joint mode was applied to fit those two outcomes jointly. The potential correlation of those two outcomes was linked by random intercepts. Information criteria (AIC and BIC) were used for model comparison and covariance structure selection. Results The small standard error of significant predictors and significant correlation between viral load and medication adherence over time provide evidence for joint model selection. The correlation between viral load and medication adherence was −0.7688 ( P -value=< 0.05), which indicates that the decrement of viral load tends to increase good medication adherence. Patient substance use, visit time, baseline CD4 cell, baseline hemoglobin, and the interaction of visit time by substance use were significantly associated with viral load and medication adherence jointly. Conclusion The study revealed that substance user adult patients, patients with low baseline CD4 cells, and patients with low baseline hemoglobin were with high viral loads and poor medication adherence. Therefore, health officials and other concerned bodies should give special attention and high intervention to patients with low baseline hemoglobin; poor adherence and low baseline CD4 cell count.

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Section: Discussionmentioning

confidence: 96%

Predictors of Viral Load and Medication Adherence Among HIV-Positive Adults Under Treatment at Felege-Hiwot Comprehensive Specialized Hospital, North-West, Ethiopia

Hussen Tale,

Tegegne,

Belay

2023

HIV

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“… 73 Additionally, substance use among WWH has been consistently associated with failure to achieve viral suppression. 74 , 75 , 76 As active viraemia is a known risk factor for kidney disease progression, 77 these may represent meaningful points of intervention as actions taken to reduce HIV stigma and eliminate barriers to clinical attendance may improve retention in care, ART adherence, and chronic disease management. Consequently, interpersonal and societal factors may compound upon and interact with each other to increase risk factors for CKD and perhaps for subsequent CKD risk.…”

Section: Discussionmentioning

confidence: 99%

Associations between female birth sex and risk of chronic kidney disease development among people with HIV in the USA: A longitudinal, multicentre, cohort study

et al. 2022

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Gendered Racial Microaggressions, Self-silencing, Substance Use, and HIV Outcomes Among Black Women Living with HIV: A Structural Equation Modeling Approach

Shahid,

Dale

2023

AIDS Behav

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Moderating effects of social support on the relationship between substance use disorders and HIV viral load and medication adherence among Black women living with HIV in the United States

Cited by 8 publications

References 48 publications

Predictors of Viral Load and Medication Adherence Among HIV-Positive Adults Under Treatment at Felege-Hiwot Comprehensive Specialized Hospital, North-West, Ethiopia

Predictors of Viral Load and Medication Adherence Among HIV-Positive Adults Under Treatment at Felege-Hiwot Comprehensive Specialized Hospital, North-West, Ethiopia

Associations between female birth sex and risk of chronic kidney disease development among people with HIV in the USA: A longitudinal, multicentre, cohort study

Gendered Racial Microaggressions, Self-silencing, Substance Use, and HIV Outcomes Among Black Women Living with HIV: A Structural Equation Modeling Approach

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