Modern aspects of nutritional support during hematopoietic stem cell transplantation: review, experience of the N.N. Petrov National Medical Research Center of Oncology

Volchenkov, S.A. Volchenkov; Lyubimov, S.V. Lyubimov; Zyuzgin, Ilya; Elkhova, S.S. Elkhova; Зверькова, А А; Ishmatova, I.; Semiglazova, Tatiana

doi:10.18565/pharmateca.2022.7.14-22

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“…Malnutrition has been proven to be a poor prognostic indicator for HSCT patients [ 19 , 25 , 26 , 27 , 28 ]. The risk of mortality might be twice as high in the HSCT when malnourished [ 15 , 27 , 29 ]. To prevent it, assembling adequate planning and support for the nutrition of patients who undergo HSCT, nutritional risk assessment, and screening are required [ 17 , 30 , 31 ].…”

Section: Nutritional Assessment and Screeningmentioning

confidence: 99%

The Critical Exploration into Current Evidence behind the Role of the Nutritional Support in Adult Patients Who Undergo Haematogenic Stem Cell Transplantation

et al. 2023

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Haematopoietic stem cell transplantation (HSCT) is a treatment option for many haematological conditions in patients of all ages. Nutritional support is important at each stage of treatment, but particular nutritional needs and dictated support occur during the preparatory (conditioning regimen) and post-transplant periods. Patients may require nutritional treatment by the enteral or parenteral route. The quantitative and qualitative composition of meals may change. Vitamin requirements, including vitamin D and vitamin C, might also be different. An adequately composed diet, adapted to the needs of the patient, may influence the occurrence of complications such as graft-versus-host disease (GvHD), gastrointestinal disorders, infections, and reduced survival time. Haematological diseases as well as transplantation can negatively affect the intestinal flora, with negative consequences in the form of mucosal inflammation and disorders of a functional nature. Currently, aspects related to nutrition are crucial in the care of patients after HSCT, and numerous studies, including randomized trials on these aspects, are being conducted. This study serves the critical analysis of current scientific evidence regarding nutritional support for patients after HSCT.

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