Modern creatinine (Bio)sensing: Challenges of point-of-care platforms

Why ammonium detection is particularly challenging but insightful with ionophore-based potentiometric sensors – an overview of the progress in the last 20 years

“…Interestingly, the developed platform was applied to water monitoring (concentrations versus depth) in a natural lake over a period of 4 days. However, the NH 61 used as the standard technique was found for all the analyzed samples. Interestingly, the biosensor was found to be more reliable than the reference method in the case of nondeproteinized serum samples, probably because of the nonspecificity of the reference method for higher content of proteins in the samples.…”

Blood biomarkers for assessing headaches in healthcare workers after wearing biological personal protective equipment in a COVID-19 field-hospital

“…Various studies, such as those by Gozubatik-Celik G et al (27), in patients during dialysis, or by Poyrazoğlu HG et al (28) in an infant population, have already described this correlation between creatinine and the appearance of headaches. It should be noted that the assessment of creatinine levels using POCT is a reliable and fast method and it is performed with a simple venous analysis or capillary blood sample (29) (30). In this sense, dehydration has been related to a headache increase (31) and also to creatinine levels increase (32).…”

A novel cerium(iii)–isatin Schiff base complex: spectrofluorometric and DFT studies and application as a kidney biomarker for ultrasensitive detection of human creatinine

“…21 Around 95% of the creatine in the human body is stored in skeletal muscle and 5% is in the brain, so it is a source of energy for muscle activity and the brain. 22 Most men with normal kidney function have approximately 60 to 110 mM of creatinine and women with normal kidney function have between 45 and 90 mM of creatinine. Serum creatinine allows us to dictate the glomerular ltration rate (GFR).…”