“…But the disease is part of the patient and not the patient part of the disease, necessitating an approach to assessment and treatment that is as concerned with the patient's subjective experience of illness as it is with objective clinical and laboratory examination. Indeed, patients present for assistance not as a collection of organ systems, one or more of which may be dysfunctional requiring scientifically indicated technical and pharmacological interventions, but rather as integral human beings with narratives, values, preferences, psychology and emotionality, spiritual and existential concerns, a cultural situation, possible difficulties with sexual, relational, social and work functioning, possible alcohol and substance abuses and addictions, worries, anxieties, fears, hopes, goals and ambitions -and more [28]. As persons, patients exist not in isolation, but in relationship and community, therefore requiring not simply an analysis of their genomics, proteomics, pharmacogenomics, metabolomics and epigenomics, but a proper understanding also of their social situation and the extent to which this mediates an adequate, good or poor response to biological and related interventions [41,42].…”