Modern Management of Acute Pancreatitis

Acute Pancreatitis: What's the Score?

“…Risk factors for readmission in this study included GI symptoms at time of discharge, including nausea, vomiting, or diarrhea, discharge on less than a solid diet, and moderate to heavy alcohol use (56). Other risk factors include smoking and recurrent biliary problems (26). A subsequent study confirmed these findings and developed a scoring system to predict readmission at discharge (43).…”

“…Systemic complications include extrapancreatic infection and multi-organ failure. Patients with evidence of multiorgan failure have the highest mortality and should be managed in a critical care unit (26).…”

Bacteremia in Patients With Acute Pancreatitis as Revealed by 16S Ribosomal RNA Gene-Based Techniques*

“…The administration of prophylactic antibiotics remains controversial in the management of AP (39)(40)(41)(42)(43)(44). As the mortality of SAP is obviously associated with the complications of infection, the patients are often administrated prophylactic broad-spectrum antimicrobial agents with the aim of reducing the prevalence of pancreatic and peripancreatic infections (39,40).…”

Acute kidney injury following acute pancreatitis: A review

“…However, cross-sectional imaging in the early phase of evaluation is not associated with improved outcome, but is very important and usually used between 48-72 h after hospitalisation. Antibiotic treatment in SAP is still a controversial option and some studies recommend use of antibiotics agents only if the complications of sepsis are presented but not for their prevention [63][64][65] . In addition, broad spectrum antibiotics with good tissue penetration are necessary to prevent infection in SAP after CT-proven pancreatic necrosis 66 .…”