Modern Microwave Thermometry for Breast Cancer

Abstract

The temperature of a malignant tumour is a universal indicator of the growth rate of the tumor. Tumor temperature can be used as a prediction of the benefit of individual therapies and in monitoring the efficacy of breast cancer treatment. This review provides a systematic analysis of the data available in the current literature on the role of microwave thermometry in risk estimation, the diagnosis of breast pathology and in assessing the effect of neoadjuvant therapy for breast cancer treatment.Various aspects of the use of microwave thermometry in breast diseases are described: the diagnostic value of the method and the value in differentiating hyperplasia, benign and malignant disease. Research has also suggested a prognostic role of microwave thermometry and its possible application to assess the effect of preoperative chemotherapy in locally advanced breast cancer.Microwave thermometry is a non-invasive method that can provide valuable information in relation to the diagnosis of various breast pathologies and may have value in screening programs to identify high risk groups for subsequent diagnostics using traditional methods (ultrasound, X-ray mammography, breast MRI, morphology). Microwave thermometry can also be used to assess the effect of ongoing neoadjuvant therapy of the primary nonoperative forms of breast cancer in order to allow early detection of response and provide as part of personalized medicine

AFM Imaging of Protein Aggregation in Studying the Impact of Knotted Electromagnetic Field on A Peroxidase

“…The problem of the effect of microwave radiation on enzymes is of great interest. Particularly, this concerns the power range at the level of background radiation (~10 −12 W/cm 2 ), at which the radiation in enzyme systems is registered 29 and pathological changes in human are detected 30 . The impact of microwave radiation on proteins is determined by both the radiation power and the exposure time.…”

Research of a microwave radiometer for monitoring of internal temperature of biological tissues

“…In recent years, many new publications on the use of MWR in medicine have appeared. MWR is used in mammalogy to detect breast cancer and monitor progress of treatment of various diseases of the mammary glands [1,2]. The method is used in critical care medicine to measure brain temperature during treatment of cerebral stroke and traumas [3].…”

The prospects of creating of microwave radiothermography based on monolithic integrated circuits

“…MR is used to detect cancer and monitor the course of treatment of various diseases of the mammary glands in mammology ( Fig. 1) [3][4][5][6]. In emergency medicine, the method is used to measure brain temperature in the treatment of stroke and traumatic brain injuries [7][8][9][10].…”

“…The great interest of physicians, biologists and biophysicists to microwave radiometry (MR) is due to the fact that it is a non-invasive method of measuring the deep temperatures of the internal areas of the human body based on their own thermal radiation. This method has received deserved recognition in medicine in the diagnosis of damages of the central and peripheral nervous system, assessment of local inflammatory, traumatic, oncological, vascular and dystrophic diseases of various localization [1][2][3][4][5][6].…”