The relevance of the study is related not only to the economic and demographic issues of achieving a balance of labor and human resources in the eastern territories of the country, but also to the increased need for the geopolitical stability of the Russian Federation. The article examines the features and directions of the territorial and sectoral placement of the labor force of foreign labor migrants in the Siberian Federal District. The main conclusions of the work are as follows: 1) with the existing depopulation of the population, the territory of the Siberian Federal District retains the historical orientation of the state migration policy towards the placement of labor from external territorial sources; 2) the economy of the Siberian Federal District creates employment opportunities that contribute to the attraction of foreign labor. The sectoral specifics of the application of the labor force of foreign labor migrants are represented by construction, trade and repair of cars; 3) the territorial location of foreign labor migrants is represented by their concentration in agglomerations and cities of the Siberian Federal District; 4) the population of the district is characterized by a tolerant attitude towards foreign labor migrants; 5) industry is the leading branch of the economy of the Siberian Federal District, contributes to the activation of social-economic development of the regions and their standard of living, which contributes to the influx of foreign labor migrants. The conclusions and results of the work can be useful to representatives of the real sector of the regional economy, specialists to determine the assessment of the ongoing socio-economic and migration processes in the eastern regions of the country.