Modern Size-Exclusion Liquid Chromatography (Yau, W. W.; Kirkland, J. J.; Bly, D. D.)

Abstract

This book represents an effort to present a complete description of the chemistry of silica and is a greatly expanded and updated version of a previous book by the same author ("The Chemistry of Silica and Silicates," Cornell University Press, 1955).The book is divided into seven chapters-The Occurrence, Dissolution, and Deposition of Silica, 115 pp.; Water Soluble Silicates, 55 pp.; Polymerization of Silica, 150 pp. ; Colloidal Silica-Concentrated Sols, 127 pp.; Silica Gels and Powders, 160 pp.; The Surface Chemistry of Silica, 108 pp.: and Silica in Biology, 83 pp.The author has undertaken a massive effort in summarizing and abstracting approximately three thousand references into a readable and coherent description of the chemistry of silica. The book is well-written in that sufficient detail is provided to allow one unfamiliar with a particular topic to derive a basic understanding. On the other hand, the detail presented and literature reviewed provides substantial reference material for individuals familiar with the general area. Each chapter is broken down into a number of subtopics generally covering the chemistry, physical properties, preparations when appropriate, and uses of the particular forms discussed.In summary, the book serves as a major reference work for those interested in silica. In addition, the style and detail provided make it a useful book for those with a general interest but with little or no background in the area (including undergraduates and graduate students).

Patients with IgA nephropathy have circulating anti-basement membrane antibodies reacting with structures common to collagen I, II, and IV.

“…The procedure used was modified from that of Dean et al (8). Thus, lyophilized bovine GBM was suspended in 8 M urea/0.05 M Tris HCl, pH 7.5, containing the protease inhibitors mentioned above, by using a Potter-Elvehjem homogenizer.…”

“…The Goodpasture antigen has been isolated by using such collagenase digests and found to be contained in the NC1 globular domain (6,7). The monomeric form ofthe NC1 globule can also be prepared by collagenase digestion of collagen IV a chains isolated from GBM by reduction and alkylation of disulfide bonds under denaturing conditions (6,8). Antibodies raised against subunits of the NC1 globule (9) react only with collagen IV and can be used to identify this collagen.…”

Low Temperature Molecular Adaptation of the Skeletal Muscle Sarco(endo)plasmic Reticulum Ca2+-ATPase 1 (SERCA 1) in the Wood Frog (Rana sylvatica)

“…The positive cooperativity of Ca 2ϩ binding has been proposed to be a result of protein-protein interactions (23,30). Similarly, Dean et al (19,31) have shown that solubilization of SERCA1 with the nonionic detergent C 12 E 8 results in the formation of an As a first step in reaching a molecular understanding of the enzymatic differences between R. sylvatica and R. clamitans SERCA1s, we report the complete amino acid sequences for the two proteins. Comparisons between R. sylvatica, R. clamitans, and R. esculenta indicate that there are seven amino acids in SERCA1 that are unique to R. sylvatica and, therefore, may be related to the functional differences noted above (Table I).…”

ChemInform Abstract: Fused‐Skeleton Saturated Six‐Membered 1,3‐N,O, N,N and N,S Heterocycles. Fused‐Skeleton Aryl‐Substituted Saturated Isoindolones

“…Besides the cisand transfused bicyclic pyrimidinones with different sizes of the carbocycle (133),(2812g*116) we have synthesized and studied numerous three-ring homologues. These were differently saturated stereohomogeneous derivatives, e.g.…”