Modern Techniques and Applications in Cerenkov Counting

Ross, Howard B.; Rasmussen, Gregory T.

doi:10.1016/b978-0-12-663850-9.50030-9

Cited by 6 publications

(4 citation statements)

References 25 publications

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“…Semen specimens were provided by healthy white males [18][19][20][21][22][23][24][25][26][27][28][29][30][31][32][33][34][35] years old in Chapel Hill, North Carolina. The exposure groups included 12 heavy smokers (20 or more cigarettes per day for at least 1 year), and 12 nonsmokers (less than 100 cigarettes in their lifetime) (13).…”

Section: Human Spermmentioning

confidence: 99%

Comparison of DNA adducts from exposure to complex mixtures in various human tissues and experimental systems

Lewtas

Mumford²,

Everson³

et al. 1993

Environ Health Perspect

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DNA adducts derived from complex mixtures of polycyclic aromatic compounds emitted from tobacco smoke are compared to industrial pollution sources (e.g., coke ovens and aluminum smelters), smoky coal burning, and urban air pollution. Exposures to coke oven emissions and smoky coal, both potent rodent skin tumor initiators and lung carcinogens in humans, result in high levels of DNA adducts compared to tobacco smoke in the in vitro calf thymus DNA model system, in cultured lymphocytes, and in the mouse skin assay. Using tobacco smoke as a model in human studies, we have compared relative DNA adduct levels detected in blood lymphocytes, placental tissue, bronchoalveolar lung lavage cells, sperm, and autopsy tissues of smokers and nonsmokers. Adduct levels in DNA isolated from smokers were highest in human heart and lung tissue with smaller but detectable differences in placental tissue and lung lavage cells. Comparison of the DNA adduct levels resulting from human exposure to different complex mixtures shows that emissions from coke ovens, aluminum smelters, and smoky coal result in higher DNA adduct levels than tobacco smoke exposure. These studies suggest that humans exposed to complex combustion mixtures will have higher DNA adduct levels in target cells (e.g., lung) as compared to nontarget cells (e.g., lymphocytes) and that the adduct levels will be dependent on the genotoxic and DNA adduct-forming potency of the mixture. ImagesFIGURE 1.FIGURE 1.FIGURE 2.FIGURE 3.FIGURE 3.FIGURE 3.FIGURE 3.FIGURE 3.FIGURE 3.FIGURE 4.

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Section: Human Spermmentioning

confidence: 99%

Comparison of DNA adducts from exposure to complex mixtures in various human tissues and experimental systems

Lewtas

Mumford²,

Everson³

et al. 1993

Environ Health Perspect

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“…What followed was a great deal of work aiming to leverage Cherenkov emissions to determine the radioactivity of a solution, i.e., Cherenkov counting. During this time, investigations regarding the medium effects on Cherenkov emissions were largely concerned with correcting for quenching to determine the average energy of the particle more accurately [23].…”

Section: Historical Overview (1953-1985) 21 Early Considerations On T...mentioning

confidence: 99%

“…Cherenkov counting [14,23,31], in vivo Cherenkov imaging [19,20], and Cherenkov scintillators [48,49] are all at this point in history well-established, mature topics that see widespread adoption in research, industrial, and medical applications. Cherenkov spectroscopic techniques, on the other hand, were arguably not even developed to the point of being quantitative until this century.…”

Section: Belchermentioning

confidence: 99%

Superluminal Molecular and Nanomaterial Probes Based on Fast Ions or Electrons

Morrison,

Srivatsa,

Ghandi

2024

Molecules

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This work reviews the progression of chemical analysis via Cherenkov emissions, i.e., Cherenkov Photometry and Cherenkov Emission Spectroscopy, from its introduction in the literature up to modern developments. In presenting the history of this field, we aim to consolidate the literature, both for reference and contextualization. We present an argument aiming to untangle why this corner of research has seen little progress while so many other directly related aspects of Cherenkov research have flourished, as well as speak to the progress of the field in recent years and prospective direction in years to come.

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“…Determination of the latter by Cerenkov counting is attractive, as was recognized by Yamada (1962), who obtained a detection limit of about 0.2 dpm/ml using 8-litre water samples. Ross and Rasmussen (1974) reported 36-50% efficiency for 9D Y, and Cannon (1979) described the measurement of both 89 Sr and 90 Sr, bat little attention has been given to low levels of 90 Sr-Y.…”

Section: Introductionmentioning

confidence: 99%