2015
DOI: 10.1007/s00405-015-3793-4
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Modern trends in the management of head and neck paragangliomas

Abstract: Head and neck paragangliomas (HNPG) are rare, mostly benign neoplasms that usually exhibit an indolent growth pattern although they can be associated with compression and infiltration of adjacent cranial nerves and, depending on the site of origin, also bone and intracranial structures. Less than 5 % of the tumors are considered malignant based on the presence of metastases and not local invasion. Carotid body tumors accounts for two-thirds of HNPG, whereas vagal paragangliomas are showing the highest tendency… Show more

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Cited by 6 publications
(9 citation statements)
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“…The main manifestations of carotid body tumors (CBTs) as well as jugular and tympanic PGLs must first be classified clinically, according to Shamblin for CBTs and to Fisch for jugulo-tympanic HNPs (Shamblin et al 1971, Fisch & Mattox 1988. While complete surgical resection represents the only curative treatment option for HNPs, multiple studies have demonstrated that complication rates after surgery were very much dependent on location and stage of the tumor (Suarez et al 2013(Suarez et al , 2014(Suarez et al , 2015. CBTs in Shamblin class I and II, as well as tympanic PGLs, can usually be completely resected with a very low risk of morbidity and without mortality (Suarez et al 2013(Suarez et al , 2015.…”
Section: Answer 1: Diagnosis and Management Of Head And Neck Paragangmentioning
confidence: 99%
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“…The main manifestations of carotid body tumors (CBTs) as well as jugular and tympanic PGLs must first be classified clinically, according to Shamblin for CBTs and to Fisch for jugulo-tympanic HNPs (Shamblin et al 1971, Fisch & Mattox 1988. While complete surgical resection represents the only curative treatment option for HNPs, multiple studies have demonstrated that complication rates after surgery were very much dependent on location and stage of the tumor (Suarez et al 2013(Suarez et al , 2014(Suarez et al , 2015. CBTs in Shamblin class I and II, as well as tympanic PGLs, can usually be completely resected with a very low risk of morbidity and without mortality (Suarez et al 2013(Suarez et al , 2015.…”
Section: Answer 1: Diagnosis and Management Of Head And Neck Paragangmentioning
confidence: 99%
“…While complete surgical resection represents the only curative treatment option for HNPs, multiple studies have demonstrated that complication rates after surgery were very much dependent on location and stage of the tumor (Suarez et al 2013(Suarez et al , 2014(Suarez et al , 2015. CBTs in Shamblin class I and II, as well as tympanic PGLs, can usually be completely resected with a very low risk of morbidity and without mortality (Suarez et al 2013(Suarez et al , 2015. Tumor recurrence in this group of patients is very low.…”
Section: Answer 1: Diagnosis and Management Of Head And Neck Paragangmentioning
confidence: 99%
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“…In this context, conventionally fractionated RT and radiosurgery as SRS, FSRT, or HFSRT are now considered as a viable part of multimodality TBC management. While management of advanced, incompletely resected, or recurrent lesions with irradiation has been widely accepted as common practice, accumulating evidence in favor of irradiation has been supported by several studies as well as systemic reviews and metaanalyses assessing its utility as the primary mode of management [56, [63][64][65][73][74][75][76][103][104][105][106][107][108][109][110].…”
Section: Introductionmentioning
confidence: 99%