Modest correlation between serum neopterin levels and Gensini scores in a cohort of patients undergoing coronary angiography

Özbek, C.; Baran, İbrahim; Tütüncü, Ahmet; Kuştarcı, T.; Karaagac, Kemal; Özbek, Aysun

doi:10.1007/s11845-013-1009-8

Cited by 1 publication

(1 citation statement)

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Higher neopterin concentrations were presented in coronary heart disease. Ozbek C et al performed a study with 40 stable angina pectoris patients and found a positive correlation between serum neopterin and Gensini scores as in this study [13]. High levels of neopterin may be due to inflammation, a compound of endothelial dysfunction.…”

Section: Discussionsupporting

confidence: 65%

Evaluation of Relationship Between Serum Neopterin, Cystatin C and Coronary Heart Disease

Abuşoğlu¹

2016

Ann Clin Anal Med

View full text Add to dashboard Cite

Anahtar KelimelerNeopterin; Sistatin C; Ateroskleroz; Koroner Arter Hastalığı; Gensini Skoru Abstract Aim: It has been reported that neopterin, a key molecule for immun response organization, is released from active macrophages of atheromatous plaque and useful for cardiovascular risk stratification. The aim of this study was to investigate serum cystatin C and neopterin levels in patients with coronary artery disease and examine the relationship between these markers and cardiovascular risk factors. Material and Method: Coronary artery disease group and control group consisted of 75 subjects (61 males, 14 females, mean age 60.5±10) and 50 subjects (25 males, 25 females, mean age 56.9±10), respectively. Results: Serum neopterin concentrations were higher in coronary artery disease group compared to control group. A negative correlation was established between neopterin and high density lipoprotein cholesterol. Also, there was a positive correlation between Gensini score and cystatin C and neopterin. Discussion: Serum cystatin C and neopterin concentrations might be useful markers for determining the coronary artery disease's severity. According to this study, neopterin seems to be a stronger indicator of cardiovascular diseases compared to cystatin C. The positive correlation between Gensini score and the biochemical markers offers us a potential use of these markers in evaluating the disease's severity.

show abstract

Section: Discussionsupporting

confidence: 65%

Evaluation of Relationship Between Serum Neopterin, Cystatin C and Coronary Heart Disease

Abuşoğlu¹

2016

Ann Clin Anal Med

View full text Add to dashboard Cite

show abstract

Modest correlation between serum neopterin levels and Gensini scores in a cohort of patients undergoing coronary angiography

Abstract: By the guidance of our results, we can confidently state that there is a correlation between serum neopterin levels and the severity and extent of CAD in stable coronary artery disease patients.

Cited by 1 publication

References 27 publications

Evaluation of Relationship Between Serum Neopterin, Cystatin C and Coronary Heart Disease

Evaluation of Relationship Between Serum Neopterin, Cystatin C and Coronary Heart Disease

Contact Info

Product

Resources

About