Modifiable lifestyle risk factors for dry eye disease

Wang, Michael T.M.; Müntz, Alex; Mamidi, Brinda; Wolffsohn, James S.; Craig, Jennifer P.

doi:10.1016/j.clae.2021.01.004

Cited by 47 publications

(61 citation statements)

References 41 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Sjögren's syndrome), gender, use of topical and systemic medications, advancing age, environmental or lifestyle factors (e.g. air conditioning, use of screen-based technologies), allergies and the wearing of contact lens [4][5][6][7][8].…”

Section: Abstract: Covid-19;mentioning

confidence: 99%

A Narrative Review of Current Understanding and Classification of Dry Eye Disease with New Insights on the Impact of Dry Eye during the COVID-19 Pandemic

Barabino

2021

Ophthalmol Ther

View full text Add to dashboard Cite

Dry eye disease (DED) is a complex, progressive and multifactorial condition that is commonly seen in clinical practice and can be challenging to accurately diagnose. Untreated or suboptimally managed dry eye can progress to severe, chronic disease which may become resistant to treatment. Symptoms include ocular irritation and visual impairment. Patients frequently report negative consequences regarding quality of life (QoL), productivity and psychological wellbeing. Certain lifestyle factors (e.g. use of screen-based devices, air conditioning) can induce or exacerbate symptoms of DED, leading to progressive and debilitating complications. Exposures to such triggers are likely to have increased significantly during the ongoing COVID-19 pandemic with people across the

show abstract

Section: Abstract: Covid-19;mentioning

confidence: 99%

A Narrative Review of Current Understanding and Classification of Dry Eye Disease with New Insights on the Impact of Dry Eye during the COVID-19 Pandemic

Barabino

2021

Ophthalmol Ther

View full text Add to dashboard Cite

show abstract

“…One-half of subjects in this study reported at least 5 hours of daily screen time. Prolonged digital exposure time was a significant risk factor for DED in several studies, [37][38][39][40] and significantly shorter TBUT times were observed in patients with ≥8 hours of daily screen time. 40 Smartphone usage was strongly associated with paediatric DED.…”

Section: Discussionmentioning

confidence: 94%

Economic burden and loss of quality of life from dry eye disease in Canada

Chan

Ziai

Myageri³

et al. 2021

BMJ Open Ophth

View full text Add to dashboard Cite

ObjectiveTo describe the direct and indirect cost estimates of dry eye disease (DED), stratified by disease severity, and the impact of DED on quality of life (QoL) in Canadian patients.Methods and analysisA prospective, multicentre, observational, cross-sectional study was conducted at six sites across Canada. Eligible patients completed a 20 min survey on demography, general health, disease severity, QoL and direct (resource utilisation and out-of-pocket expenses for the past 3–24 months) and indirect costs (absenteeism and presenteeism based on Work Productivity and Activity Impairment questionnaire responses). Subgroup analyses were performed according to DED severity and presence of Sjögren’s syndrome.ResultsResponses from 146 of 151 participants were included in the analysis. DED was rated as moderate or severe by 19.2% and 69.2% of patients, respectively. Total mean annual costs of DED were $C24 331 (Canadian dollars) per patient and increased with patient-reported disease severity. Mean (standard deviation [SD]) indirect costs for mild, moderate and severe disease were $C5961 ($C6275), $C16 525 ($C11 607), and $C25 485 ($C22,879), respectively. Mean (SD) direct costs were $C958 ($C1216), $C1303 ($C1574) and $C2766 ($C7161), respectively. QoL scores were lowest in patients with Sjögren’s syndrome (8.2% of cohort) and those with severe DED.ConclusionThis study provides important insights into the negative impact of DED in a Canadian setting. Severe DED was associated with higher direct and indirect costs and lower QoL compared with those with mild or moderate disease. Increased costs and poorer QoL were also evident for patients with DED plus Sjögren’s syndrome versus DED alone.

show abstract

“… Inomata et al 2020 30 Adults (N=4454) Greater than 8 hours per day of screen exposure was associated with symptomatic dry eye (OSDI total score ≥13; OR=1.55) compared to less than 4 hours. Wang et al 2021 33 Individuals ≥16 years of age (N=322) Greater digital screen time per day was a risk factor for DED (OR=1.14). Wolffsohn et al 2021 34 Adults and children (N=1125) Digital screen time per day was a risk factor for DED (OR=1.09) and for evaporative DED (OR=1.08).…”

Section: Relationship Between Digital Screen Use and Dry Eye Diseasementioning

confidence: 99%

“…Wang et al 2021 33 Individuals ≥16 years of age (N=322) Greater digital screen time per day was a risk factor for DED (OR=1.14).…”

Section: Relationship Between Digital Screen Use and Ocular Surface Measuresmentioning

confidence: 99%

“…30 Evidence also supports a relationship between duration of digital screen use and diagnosed DED. [31][32][33][34] The OSAKA study (N=561) demonstrated that office workers who used digital screens for >8 hours per day had a higher risk of definite or probable DED (OR=1.94). 31 Furthermore, the JPHC-NEXT study (N=102,582) found that greater digital screen use was associated with a higher risk of clinically diagnosed DED (OR=1.18 for each 1 hour/day increment) and severe symptoms of dry eye (OR=1.11 for men and OR=1.12 for women for each 1 hour/day increment).…”

Section: Relationship Between Digital Screen Use and Dry Eye Diseasementioning

confidence: 99%

See 1 more Smart Citation

The Relationship Between Dry Eye Disease and Digital Screen Use

Al-Mohtaseb¹,

Schachter

Lee³

et al. 2021

OPTH

View full text Add to dashboard Cite

Dry eye disease is characterized by tear film instability that can result in ocular surface damage. Patients with dry eye disease may experience ocular pain/discomfort and visual disturbances that may negatively impact quality of life. Increased use of digital screens for work, communication, and entertainment, especially during times of pandemic, may contribute to dry eye. Extensive cross-sectional studies have shown that digital screen use duration is associated with an increased risk of severe symptoms and clinical diagnosis of dry eye disease in adults. Smartphone use duration has also been found to be greater in school-age children with dry eye disease than in those without dry eye disease. A commonly accepted hypothesis for the relationship between digital screen use and dry eye disease is that digital screen use changes blinking dynamics, leading to ocular dryness. This review describes evidence that digital screen use is associated with dry eye disease, that digital device use alters blinking dynamics, and that dry eye affects mental health and work productivity in digital screen users. Helpful prevention and management strategies for dry eye disease exist for those who use digital screens.

show abstract

Modifiable lifestyle risk factors for dry eye disease

Cited by 47 publications

References 41 publications

A Narrative Review of Current Understanding and Classification of Dry Eye Disease with New Insights on the Impact of Dry Eye during the COVID-19 Pandemic

A Narrative Review of Current Understanding and Classification of Dry Eye Disease with New Insights on the Impact of Dry Eye during the COVID-19 Pandemic

Economic burden and loss of quality of life from dry eye disease in Canada

The Relationship Between Dry Eye Disease and Digital Screen Use

Contact Info

Product

Resources

About