“…In this issue of the Lancet Regional Health-Europe , Mukherjee et al. 4 present a timely challenge to the prevailing view with a compelling, large-scale, retrospective, observational analysis of several modifiable risk factors. Using data from a large UK primary care database, the authors utilised a sophisticated multilevel generalised linear mixed model to analyse over 2 million asthma patients over four years: pre-pandemic (2019) and during the pandemic (2020–2022).…”