2023
DOI: 10.1111/ene.15737
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Modifiable vascular risk factors in patients with cerebral and spinal cavernous malformations: a complete 10‐year follow‐up study

Abstract: Background and purpose The aim was to investigate the effect of modifiable vascular risk factors on the risk of first and recurrent bleeding for patients with a cavernous malformation (CM) of the central nervous system (CNS) over a 10‐year period. Methods A retrospective review of our CM institutional database was performed spanning from 2003 to 2021. The inclusion criteria were non‐missing serial magnetic resonance imaging studies and clinical baseline metrics such as vascular risk factors. The exclusion crit… Show more

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Cited by 5 publications
(5 citation statements)
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“…These results are similar to those recently published by Rauscher et al, 19 which found that none of the modifiable vascular risk factors showed a strong indication for influencing hemorrhage risk. Their findings may only suggest a more aggressive course in patients with active nicotine abuse or diabetes.…”
Section: Discussionsupporting
confidence: 92%
“…These results are similar to those recently published by Rauscher et al, 19 which found that none of the modifiable vascular risk factors showed a strong indication for influencing hemorrhage risk. Their findings may only suggest a more aggressive course in patients with active nicotine abuse or diabetes.…”
Section: Discussionsupporting
confidence: 92%
“…To this extent, our study tried to analyze the natural course of conservatively treated patients with CM over an unprecedented long and complete follow-up period. Based on one of our previous studies examining the impact of vascular risk factors on bleeding risk in CM patients over 10 years, we assessed the cumulative incidence of hemorrhage and recurrent hemorrhage and examined possible risk factors for bleeding events 21 .…”
Section: Discussionmentioning
confidence: 99%
“…In this observational cohort study, data were collected ambispectively, with a large proportion of data collected prospectively and a small proportion collected retrospectively. Part of the data was taken from the data of Rauscher and colleagues 21 . Screening for more suitable patients, we investigated all consecutive CM patients admitted to our department between 2003 and 2021.…”
Section: Methodsmentioning
confidence: 99%
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