Modification and Bioactivities of Polysaccharide extracted from Mangifera Indica gum (Mango)

Abstract

Natural polysaccharides own properties like biocompatibility, biodegradability, nontoxic and inexpensive material, gaining attention for biomedical applications. Mangifera indica gum is an excellent source of polysaccharides. The present research is aimed to investigate the impact of modification on polysaccharides extracted from Mangifera indica gum. Polysaccharide extracted from Mangifera indica gum was subjected to modification through the acrylamide grafting method to enhance the functionality of natural polysaccharide. It was noted that for 100 grams of dried mango gum, 12 grams of modified polysaccharide and 15 grams of crude polysaccharide were produced. Characterization techniques such as FTIR was used to determine the functional groups on the structure of polysaccharide. The surface morphology and crystalline structure were elucidated from SEM, EDX, and XRD. The antioxidant and antibacterial activity of native and modified polysaccharides was studied. The results thus obtained were statistically analyzed and reported. The modification of native polysaccharides was expected to find low antioxidant activity after modification but gum polysaccharides did not show any antibacterial activity against Escherichia coli, Pseudomonas sp., Bacillus sp., and Staphylococcus aureus in both native and modified polysaccharides.