Modification of a gas chromatography/atmospheric pressure chemical ionisation time-of-flight mass spectrometer as an alternative to automated atmospheric pressure solids analysis probe

Stokes, Peter E.; Parker, David; Mosely, Jackie A.

doi:10.1002/rcm.6992

Cited by 1 publication

(1 citation statement)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Ultimately, ASAP is well suited to the fast analysis of solids or solutions, 20,21 the former being advantageous to the study of solvent-sensitive compounds. Our development, described herein, is designed to work interchangeably with standard ASAP, providing rapid throughput for samples that include solid air-/moisture-/solvent-sensitive samples, and has been termed inert atmospheric pressure solids analysis probe ( i ASAP).…”

Section: Introductionmentioning

confidence: 99%

Analysis of air-, moisture- and solvent-sensitive chemical compounds by mass spectrometry using an inert atmospheric pressure solids analysis probe

Mosely

Stokes

Parker

et al. 2017

Eur J Mass Spectrom (Chichester)

Self Cite

View full text Add to dashboard Cite

A novel method has been developed that enables chemical compounds to be transferred from an inert atmosphere glove box and into the atmospheric pressure ion source of a mass spectrometer whilst retaining a controlled chemical environment. This innovative method is simple and cheap to implement on some commercially available mass spectrometers. We have termed this approach inert atmospheric pressure solids analysis probe ( iASAP) and demonstrate the benefit of this methodology for two air-/moisture-sensitive chemical compounds whose characterisation by mass spectrometry is now possible and easily achieved. The simplicity of the design means that moving between iASAP and standard ASAP is straightforward and quick, providing a highly flexible platform with rapid sample turnaround.

show abstract

Section: Introductionmentioning

confidence: 99%