Modification of carboxyl‐functionalized single‐walled carbon nanotubes with biocompatible, water‐soluble phosphorylcholine and sugar‐based polymers: Bioinspired nanorods

Abstract

We report here the successful functionalization of single-walled carbon nanotubes with bioinspired sugar and phosphocholine polymeric structures via surface-initiated atom transfer radical polymerization. The surface-polymer-coated carbon nanotubes have been systematically analyzed by Raman, infrared, ultravioletvisible, and nuclear magnetic resonance spectroscopy and high-resolution transmission electron microscopy, which give strong evidence of successful functionalization. The successful aqueous dispersion of the functionalized carbon nanotubes also indicates that functionalization has been achieved. ) are thanked for their assistance with high-resolution transmission electron microscopy, differential scanning calorimetry/thermogravimetric analysis, and Raman analyses, respectively. Finally, S. P. Armes (Department of Chemistry, University of Sheffield) is acknowledged for his comments and critical reading of the manuscript.

Synthesis and characterization of sugar-based methacrylates and their random copolymers by ATRP

“…In this study, four different sugar-based methacrylates were firstly synthesized by two-step method: to acetal groups (>CHCCl 3 ) were assigned at 5.60, 5.66, 5.30 and 5.40 ppm, whereas the H-1 protons were detected at 6.21, 5.92, 6.10 and 6.19 ppm. These shifts were in accordance with the literature data that were reported similar furanosidic trichloroethylidene acetals [46][47][48][49][50]. On the other hand, the characteristic protons of double bond and methyl groups of methacrylate were detected between 5.57-6.13 and 1.93-1.95 ppm, which confirmed the presence of methacrylate moieties on the monosaccharides.…”

An Introduction to Bio‐nanohybrid Materials

“…In this way, p-N-acryloamidophenyl a-Dglucopyranoside has been assembled with SWCNTs (Figure 1.14A) with the aim being to create materials able to show specific interaction with carbohydrate recognition proteins, which can be of interest for the recognition of bacterial toxins and viral proteins, or quantitative estimation of carbohydrate-carbohydrate interactions [195]. Functionalization of SWCNTs via atom transfer radical polymerization (Figure 1.14B) allows the direct grafting of sugar-and phosphorylcholine-based biopolymers, making the modified CNTs water soluble and biocompatible [35]. Interestingly, the resulting bio-nanocomposites based on the anchorage of the sugar moiety may have interest in carbohydrate-protein recognition, whereas the phosphorylcholine derivative could prevent nonspecific protein adsorption and cellular adhesion.…”

“…This biohybrid is able to specifically recognize the lectin Helix pomatia agglutinin (Figure 1.15A). Galactose-modified CNTs are able to capture [195] with permission from Elsevier, and (B) from [35] reproduced by permission of Wiley-VCH. [192] (reproduced by permission of Wiley-VCH) and (B) from [194] (reproduced by permission of The Royal Society of Chemistry).…”

“…Although to only a minor extent, other mechanisms can be invoked, as for instance covalent bonding (grafting) between hydroxy groups on the surface of the inorganic substrates and functional groups of the biopolymers [35].…”

Surface grafting of polyimide onto silicon surface: Preparation and characterization

“…[1][2][3][4][5][6] As single-crystal silicon is a material most used in modern microelectronics, extensive studies on incorporation of polymer chains to silicon surfaces have been reported to modify the surface physicochemical properties of silicon single crystal. Surface-initiating radical polymerization from silicon surfaces was reported by Prucker and Rü he.…”