Modification of chicha gum: Antibacterial activity, ex vivo mucoadhesion, antioxidant activity and cellular viability

Freitas, Alessandra Russo de; Ribeiro, Antônio J.; Ribeiro, Alessandra Braga; Collado-Gonzalez, Maria Del Mar; Silva, Luís; Alves, L.C.; Melro, Elodie; Antunes, Filipe E.; Veiga, Francisco; Morais, Alan Ícaro Sousa; Bezerra, Roosevelt D.S.; Soares-Sobrinho, José Lamartine; Osajima, Josy Anteveli; Silva-Filho, Edson C.

doi:10.1016/j.ijbiomac.2022.12.204

Cited by 10 publications

(1 citation statement)

References 51 publications

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“…The most industrially used gums are Starch, Cellulose, Guar gum, Arabic gum, Goethe, Korean, Tragacanth, Galena, and Agar. However, the search for new gums with special properties has aroused interest in the scientific community [5][6][7].…”

Section: Introductionmentioning

confidence: 99%

Influence of Reduction with NaBH4 and HCl in Obtaining Amino Derivatives of Cashew Gum and Cytotoxic Profile

Brito,

Lopes,

Ribeiro

et al. 2023

Polymers

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Tree-exuded gums are natural polymers that represent an abundant raw material in the food and pharmaceutical industries. The cashew gum can be obtained by exudation of trees of the genus Anacardium, a native species of the Brazilian northeast; its polymer consists of monosaccharide units propitious to the action of chemical reactions that tend to improve their intrinsic characteristics among them, as the degree of hydro-solubility. The objective of this work was to modify the exudate gum of Anacardium occidentale (cashew gum (CG)) through an amine reaction. The modification was confirmed by Nuclear Magnetic Resonance (1H NMR), infrared spectroscopy (FTIR), gel permeation chromatography (GPC), zeta potential, and thermogravimetric analysis (TG). In addition, the chemical modification altered the molar mass and surface charge of the CG, and the amino group binding to the CG polymers was confirmed by FTIR spectra. In addition, cytotoxicity tests were performed where cell viability was estimated by an MTT assay on RAW 264.7 macrophages. Through these tests, it was found that the amine caused an increase in the thermal stability of the amino compounds and did not present cytotoxic potential at concentrations below 50.0 mg/L.

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Section: Introductionmentioning

confidence: 99%

Influence of Reduction with NaBH4 and HCl in Obtaining Amino Derivatives of Cashew Gum and Cytotoxic Profile

Brito,

Lopes,

Ribeiro

et al. 2023

Polymers

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A Review on the Phytochemistry and Pharmacology of the Genus Sterculia

Wang,

Yan,

Hao

et al. 2024

Chemistry & Biodiversity

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The Sterculia genus is comprised of approximately 300 species, which have been widely used as traditional medicines to treat inflammation, snake bites, gastrointestinal diseases, skin diseases, microbial infections and many other diseases. To gain a comprehensive understanding of the therapeutic potential of Sterculia plants, an extensive literature search was conducted in CNKI, Bing, Wanfang Database, Springer Database, Elsevier Database, Google Scholar, Baidu Scholar, PubMed, and other similar websites from January 1971 to March 2024. The research indicated that Sterculia species predominantly contain flavonoids, terpenoids, phenylpropanoids, fatty acids, alkaloids and other chemical components. A wide range of pharmacologic activities such as anti‐inflammatory, antioxidant, antibacterial and other biological activities have been reported. Nevertheless, there isn't much scholarly research on the therapeutic material basis of the genus Sterculia. This review reports the ethnobotany, phytochemicals, and biological activities of the plants in the Sterculia genus as herbal remedies.

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Potential Uses of Polysaccharides from Plant Exudates for Treating Gastrointestinal Diseases

de Sá Guimarães Nolêto,

de Sousa Chaves,

de Oliveira

et al. 2024

Rev. Bras. Farmacogn.

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Modification of chicha gum: Antibacterial activity, ex vivo mucoadhesion, antioxidant activity and cellular viability

Cited by 10 publications

References 51 publications

Influence of Reduction with NaBH4 and HCl in Obtaining Amino Derivatives of Cashew Gum and Cytotoxic Profile

Influence of Reduction with NaBH4 and HCl in Obtaining Amino Derivatives of Cashew Gum and Cytotoxic Profile

A Review on the Phytochemistry and Pharmacology of the Genus Sterculia

Potential Uses of Polysaccharides from Plant Exudates for Treating Gastrointestinal Diseases

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