Modification of chitosan membrane with poly(vinyl alcohol) and biocompatibility evaluation

Zhuang, Peng‐Yu; Li, You-Liang; Fan, Li; Lin, Jun; Hu, Qiaoling

doi:10.1016/j.ijbiomac.2012.01.026

Cited by 81 publications

(29 citation statements)

References 35 publications

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“…This could be due to high molecular weight (190–310 kDa) and hard backbones of CS compared to PVA. Eventually, the addition of PVA into the CS polymer matrix could largely affect the CS polymer’s flexibility with only variations of a small change in tensile strength [33]. The TS showed the highest value when 0.5 wt % of TOCNs was added into PVA/CS = 25/75, PVA/CS = 50/50, and PVA/CS = 75/25 films.…”

Section: Resultsmentioning

confidence: 99%

Preparation and Characterization of Polyvinyl Alcohol-Chitosan Composite Films Reinforced with Cellulose Nanofiber

et al. 2016

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In this study microcrystalline cellulose (MCC) was oxidized by 2,2,6,6-tetramethylpiperidine-1-oxyl radical (TEMPO)-mediated oxidation. The treated cellulose slurry was mechanically homogenized to form a transparent dispersion which consisted of individual cellulose nanofibers with uniform widths of 3–4 nm. Bio-nanocomposite films were then prepared from a polyvinyl alcohol (PVA)-chitosan (CS) polymeric blend with different TEMPO-oxidized cellulose nanofiber (TOCN) contents (0, 0.5, 1.0 and 1.5 wt %) via the solution casting method. The characterizations of pure PVA/CS and PVA/CS/TOCN films were performed in terms of field emission scanning electron microscopy (FESEM), tensile tests, thermogravimetric analysis (TGA), Fourier transform infrared spectroscopy (FTIR), and X-ray diffraction (XRD). The results from FESEM analysis justified that low loading levels of TOCNs were dispersed uniformly and homogeneously in the PVA-CS blend matrix. The tensile strength and thermal stability of the films were increased with the increased loading levels of TOCNs to a maximum level. The thermal study indicated a slight improvement of the thermal stability upon the reinforcement of TOCNs. As evidenced by the FTIR and XRD, PVA and CS were considered miscible and compatible owing to hydrogen bonding interaction. These analyses also revealed the good dispersion of TOCNs within the PVA/CS polymer matrix. The improved properties due to the reinforcement of TOCNs can be highly beneficial in numerous applications.

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Section: Resultsmentioning

confidence: 99%

Preparation and Characterization of Polyvinyl Alcohol-Chitosan Composite Films Reinforced with Cellulose Nanofiber

et al. 2016

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“…Figure 4 shows the comparative XRD spectra of two membranes (CS and CS/PVA) with higher intensity of two main diffraction peaks at 2θ angle of 10.02° and 20.1° in the CS membrane indicating the conformational transition of the polymers within the blend membrane (36).…”

Section: Resultsmentioning

confidence: 99%

Evaluating the potential of chitosan/poly(vinyl alcohol) membranes as alternative carrier material for proliferation of Vero cells

et al. 2015

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Chitosan/poly(vinyl alcohol) (CS/PVA) blend membranes were prepared using the casting method and their physiochemical properties were analyzed using Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), differential scanning calorimetry (DSC) and X-ray diffraction (XRD). FTIR and XRD demonstrated possible hydrogen bonds between CS and PVA. The addition of PVA to CS resulted in surface roughness as analyzed by SEM. The CS/PVA blend membrane exhibited high tensile properties (81.62%) and reduced water-holding capacity (53.8%) compared to a pure CS membrane (control). Cell viability and proliferation were assessed via an MTT assay with Vero cell culture. Associated with improved physicochemical properties, the CS/PVA blend membrane promotes cell proliferation of Vero cells with high specific growth rate (0.582 day -1 ). The results demonstrate that the blending of CS and PVA could significantly alter the surface rugosity, water-holding capacity and improve the mechanical and biological properties of the membrane. Interestingly, this concept can be extended for different anchorage-dependent cell lines, as an alternative carrier material.

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“…With addition of PVA into chitosan, a new peak appeared at 1437 cm -1 which were caused by -CH-OH bending vibration of PVA. Also, an increase in the intensity of CH group peak at around 2928 cm -1 was observed as PVA added into chitosan blend (Zhuang et al 2012). In Figure 2, with glutaraldehyde crosslinking, PVA-g-CH shows an increment in the absorption peak of 1655 cm -1 due to N=C bonds shoulders at 1562 and 1720 cm -1 due to ethylene and free aldehydes bonds, respectively.…”

Section: Ftir Spectra Of Filmmentioning

confidence: 95%

Immobilization of Bovine Serum Albumin on the Chitosan/PVA Film

Khairuddin¹,

Afifi²,

Hashim³

et al. 2018

JSM

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Modification of chitosan membrane with poly(vinyl alcohol) and biocompatibility evaluation

Cited by 81 publications

References 35 publications

Preparation and Characterization of Polyvinyl Alcohol-Chitosan Composite Films Reinforced with Cellulose Nanofiber

Preparation and Characterization of Polyvinyl Alcohol-Chitosan Composite Films Reinforced with Cellulose Nanofiber

Evaluating the potential of chitosan/poly(vinyl alcohol) membranes as alternative carrier material for proliferation of Vero cells

Immobilization of Bovine Serum Albumin on the Chitosan/PVA Film

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