Modification of Cotton Fabric with Molecularly Imprinted Polymer-Coated Carbon Dots as a Sensor for 17 α-methyltestosterone

Abstract

Molecularly imprinted polymers@ethylenediamine-modified carbon dots grafted on cotton fabrics (MIPs@EDA-CDs/CF) and smartphone-based fluorescence image analysis were proposed and used for the first time for the detection of 17 α-methyltestosterone (MT). The EDA-CDs were synthesized and grafted on cotton fabric before coating with the MIPs. The MIPs were synthesized using the MT as a template molecule, methacrylic acid (MAA) as a functional monomer, ethylene glycol dimethacrylate (EGDMA) as a cross-linker, and azobisisobutyronitrile (AIBN) as an initiator. The MIPs@EDA-CDs/CF were characterized using FTIR, SEM-EDS, and RGB fluorescence imaging. The fluorescence images were also taken using a smartphone and the ImageJ program was used for RGB measurement. The Δ red intensity was linearly proportional to MT concentration in the range of 100 to 1000 μg/L (R2 = 0.999) with a detection limit of 44.4 μg/L and quantification limit of 134 μg/L. The MIPs@EDA-CDs/CF could be stored at 4 °C for a few weeks and could be reused twice. The proposed method could apply for the specific determination of MT in water and sediment samples along with satisfactory recoveries of 96–104% and an acceptable relative standard deviation of 1–6% at the ppb level.

Fabrication of molecularly imprinted cotton fibers for quantification of streptomycin in honey samples

“…The morphology of the CF samples was investigated by SEM and corresponding SEM images are shown in Figure 3. The pristine CF had a relatively smooth surface (Figure 3a) after pretreatment with NaOH (aq) , most probably due to removal of impurities from the cotton sample 44 . After CTA attachment (Figure 3b), there was no remarkable morphological changes observed due to the very thin layer of CTA on the CF.…”

“…The pristine CF had a relatively smooth surface (Figure 3a) after pretreatment with NaOH (aq) , most probably due to removal of impurities from the cotton sample. 44 After CTA attachment (Figure 3b), there was no remarkable morphological changes observed due to the very thin layer of CTA on the CF. This result also supports the ATR-FTIR results.…”

Distance-based paper analytical device for multiplexed quantification of cytokine biomarkers using carbon dots integrated with molecularly imprinted polymer

“…Moreover, the characteristics of the proposed dPADs were investigated using SEM images as shown and described in Fig. S5–S7 † 28,30,38,41–43.…”

“…When the target analytes selectively bind to the MIP layer through hydrogen bonding interactions and van der Waals forces, 29,33 it leads to PET between the target analytes and the CDs, resulting in the quenching of their fluorescence emission. 27,28,30,41 Similarly, the quenching system in this technique is categorized as dynamic quenching. 44,45 To verify this interaction on the developed device, we tested whether the fluorescence emission of the CDs can be changed when analytes were bound to their MIP layers and also removed.…”

Molecular imprinting of cellulose cotton fabric/silica materials with a colorimetric dithizone chelation for smartphone‐based detection of Zn (II) ions in water samples

“…It predominantly contains the most common biopolymer cellulose and noncellulosic components surrounding the cellulose core, such as hydrophobic impurities (waxes, pectins and proteins). [32][33][34] These are low-cost and portable substrates, and their functionality can be simply modified with various chemical reagents to enhance their value and usage. As a result of this modification, their applications have recently been conducted in areas of sensor technology.…”