Modification of Quartz Crystal Microbalance Surfaces via Electrospun Nanofibers Intended for Biosensor Applications

Hydrophobic and thermal behaviour of nylon 6 nanofibre web deposited on cotton fabric through electrospinning

“…Such protective wear should use fabrics having good fire protection and water-repellent properties. Many high-performance synthetic fibres such as Teflon, Twaron and Nomex have been used for this purpose [1][2][3][4]. Most commonly used wear such as cotton fabrics are made up of cellulose fibre that has poor fire-protection ability and is hydrophilic [5].…”

Plasma Polymerized Films for Mass Sensitive Biosensors

“…In the literature, plasma modified mass sensitive biosensors used in biomedical application have been presented for detecting genetically modified organism, human pathogen and mostly model protein, bovine serum albumin (BSA) over the past decade [14,19,[29][30][31][32]. A DNA biosensor, which uses single-stranded DNA probe to detect human pathogen, Vibrio parahaemolyticus, based on a quartz crystal microbalance has been used.…”

“…Then, nanofibers located on QCM were modified with allylamine monomer using plasma polymerization technique. The performance of modified QCM was tested with model protein, BSA and 548 ± 4 Hz and 50 ± 5 Hz frequency shifts were obtained for "dip and dry" method and "flow-cell method", respectively [19]. Our research group conducted a novel research to understand the effect of plasma-polymerized amine-rich thin films over QTF surfaces and to test their usability as a mass sensitive biosensor.…”

“…Many polymeric layers such as cellulose acetate, polyurethane, polystyrene, polyethylene amine, polybutyl methacrylate, polyvinyl formal/ethylal, polyvinylalcohol, and polyethyleneimine have been used for the creation of interface for immobilization of bioreceptor [15][16][17][18][19][20][21][22]. Additionally, many coating methods like silanization, immobilization on the pre-coated crystal, entrapment, or cross-linking methods are used to immobilize bioreceptor such as antibody, aptamer and nucleic acids onto the quartz crystal [6,16,[18][19][20][22][23][24]. However, at the end of these techniques, thicker films are obtained on the crystals' surfaces which diminishes performance by mass overload, and create a harsh environment, which reduces biological activity.…”

“…Nowadays, plasma technologies have been started to be used for the modification of the surface of the quartz crystal [14,19,[25][26][27][28][29][30][31][32]. This technique give chance to cover the crystal surfaces with control film growth down to the angstrom (Å) scale with uniform coating, while preserving the bulk properties of the substrate material.…”