Modified Chitosan Hydrogels and Nano Hydrogels for Congo Red Removal from Aqueous System

khaled, shimaa; Zaky, Howida T.; Nasr, Abeer Salah; Hassan, Nadia

doi:10.21608/jsrs.2021.85083.1060

Cited by 1 publication

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“…The hydrophilic functional groups in the polymer structure are responsible for the high water absorption capacity. The amount of water absorption depends on the chemical composition of the synthetic polymer or biopolymer, the crosslinking density and the environmental conditions [17,18]. Because of their typical moist and soft properties, which are highly comparable to biological tissue, hydrogels have been widely used in many biomedical applications [19].…”

Section: Introductionmentioning

confidence: 99%

Graphene-based hydrogel silver nano-composites for antibacterial and antitumor applications: In vitro evaluation

Atef,

Mostafa,

El-Sherif

2023

Journal of Scientific Research in Science

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The efficiency of most cancer therapies and antibiotics is restricted due to several issues, including medication resistance and non-specific negative effects. Hydrogels based on graphene derivative and silver nano-particles (Ag-NPs) have been employed to overcome these limitations. In this manuscript, we synthesized gelatin methacryloyl (Gel-MA) to combine with functional nano-materials. Reduced graphene oxide (rGO) was synthesized by utilising ascorbic acid as a green reductant to form a composite with Gel-MA without affecting its unique characteristics. The prepared rGO and nano-composite hydrogels were characterized by the usual characteristic spectroscopic techniques. We found that the nano-composite swelled up to 2444% due to the high porosity of the hydrogel. The results demonstrated that the nanocomposite hydrogel showed higher antimicrobial activities than virgin (Gel-MA). The cytotoxicity of Gel-MA/rGO and Gel-MA/rGO/Ag composites against human lung cancer (A549) cells was evaluated using MTT assay. The Gel-MA/rGO/Ag composite showed remarkable cytotoxicity with an IC50 of 27µg/ml towards A549 cells compared with 109µg/ml of Gel-MA/rGO.

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Section: Introductionmentioning

confidence: 99%