Modified endoscopic ultrasound-guided selective N-butyl-2-cyanoacrylate injections for gastric variceal hemorrhage in left-sided portal hypertension: A case report

Yang, Jian; Zeng, Yan; Zhang, Junwen

doi:10.12998/wjcc.v10.i18.6254

Cited by 3 publications

(1 citation statement)

References 17 publications

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“…The vascular complications are splenic artery pseudoaneurysm and thrombosis of the splenic vein or peripancreatic branches of the portal system, with development of left-sided portal hypertension. Bleeding from gastric varices due to left sided portal hypertension or ectopic varices can be easily localized and treated (in experienced hands) with EUS-guided coil and glue injection [47].…”

Section: Eus For the Treatment Of Vascular Complications Of Acute Pan...mentioning

confidence: 99%

Endoscopic Ultrasound in Pancreatology: Focus on Inflammatory Diseases and Interventions

Vitali,

Zundler,

Jesper

et al. 2023

Visc Med

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Background: Endoscopic ultrasound (EUS) is a main tool in pancreatology for both diagnosis and therapy. It allows minimally invasive differentiation of various diseases, with a minimal degree of inflammation or anatomic variations. EUS also enables interventional direct access to the pancreatic parenchyma and the retroperitoneal space, the pancreatic duct, the pancreatic masses, cysts, vascular structures for diagnostic and therapeutic purposes. Summary: This review aimed to summarize the new developments of EUS in the field of pancreatology, with special interest on inflammation and interventions. EUS enables way to perform pseudocyst drainage, necrosectomy, transenteral drainage and transenteric access of the main pancreatic duct, or the direct visualization or therapy of vascular structures adjacent to the pancreas. Key Messages: EUS has a deep impact on pancreatology, and the development of new diagnostic and interventional approaches to the retroperitoneal space and the pancreas has increased in the last years exponentially, allowing minimal invasive diagnostics and therapy and avoiding surgery and percutaneous therapy.

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Section: Eus For the Treatment Of Vascular Complications Of Acute Pan...mentioning

confidence: 99%

Endoscopic Ultrasound in Pancreatology: Focus on Inflammatory Diseases and Interventions

Vitali,

Zundler,

Jesper

et al. 2023

Visc Med

View full text Add to dashboard Cite

show abstract

Endoscopic ultrasound-guided diagnosis and treatment of gastric varices

Yang¹,

Zeng²,

Zhang³

2022

World J Gastrointest Endosc

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Safety and efficacy of modified endoscopic ultrasound-guided selective N-butyl-2-cyanoacrylate injections for gastric variceal hemorrhage in left-sided portal hypertension

Zeng,

Yang,

Zhang

2024

World J Gastrointest Endosc

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BACKGROUND Gastric variceal hemorrhage is one of the primary manifestations of left-sided portal hypertension (LSPH). The hemorrhage is fatal and requires safe and effective interventions. AIM To evaluate the clinical safety and efficacy of modified endoscopic ultrasound (EUS)-guided selective N-butyl-2-cyanoacrylate (NBC) injections for gastric variceal hemorrhage in LSPH. METHODS A retrospective observational study of patients with LSPH-induced gastric variceal hemorrhage was conducted. Preoperative EUS evaluations were performed. Enrolled patients were divided into modified and conventional groups according to the NBC injection technique. The final selection of NBC injection technique depended on the patients’ preferences and clinical status. The technical and clinical success rates, operation time, NBC doses, perioperative complications, postoperative hospital stay, and recurrent bleeding rates were analyzed, respectively. RESULTS A total of 27 patients were enrolled. No statistically significant differences were observed between the two groups regarding baseline characteristics. In comparison to patients in the conventional group, patients in the modified group demonstrated significantly reduced NBC doses (2.0 ± 0.6 mL vs 3.1 ± 1.0 mL; P = 0.004) and increased endoscopic operation time (71.9 ± 11.9 min vs 22.5 ± 6.7 min; P < 0.001). Meanwhile, the two groups had no significant difference in the technical and clinical success rates, perioperative complications, postoperative hospital stay, and recurrent bleeding rates. CONCLUSION Modified EUS-guided selective NBC injections demonstrated safety and efficacy for LSPH-induced gastric variceal hemorrhage, with advantages of reduced injection dose and no radiation risk. Drawbacks were time consumption and technical challenge.

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Modified endoscopic ultrasound-guided selective N-butyl-2-cyanoacrylate injections for gastric variceal hemorrhage in left-sided portal hypertension: A case report

Cited by 3 publications

References 17 publications

Endoscopic Ultrasound in Pancreatology: Focus on Inflammatory Diseases and Interventions

Endoscopic Ultrasound in Pancreatology: Focus on Inflammatory Diseases and Interventions

Endoscopic ultrasound-guided diagnosis and treatment of gastric varices

Safety and efficacy of modified endoscopic ultrasound-guided selective N-butyl-2-cyanoacrylate injections for gastric variceal hemorrhage in left-sided portal hypertension

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