Modified graphene based molecular imprinted polymer for electrochemical non-enzymatic cholesterol biosensor

Ultrasensitive Bioaffinity Electrochemical Sensors: Advances and New Perspectives

“…Several transducers were developed monitoring the binding process and transforming it into a processable signal. electrocatalytical activity, which limited the MIPs applications in electrochemical sensing and biosensing [115]. However, more MIPs prepared by the conventional technique have few disadvantages such as low-affinity binding, incomplete template removal, high diffusion barrier and slow mass transfer, lack of conductivity and Abbreviations: Ab(O157) or Ab(O1), antibodies for E. coli O157 : H7 or Vibrio cholerae O1; Bio-Ab, biotinylated antibodies; H1-4, hairpin nucleotide for HCR reaction; MB@SA, streptavidin-coated magnetic beads; NI1-2, nucleotide initiator; SP1-2, signal probe.…”

A colorimetric nanoprobe based on enzyme-immobilized silver nanoparticles for the efficient detection of cholesterol

“…Therefore, it is essential to detect both high and low levels of cholesterol. 15 Various methods such as electrochemical sensing [16][17][18][19][20][21][22] uorometric analysis, [23][24][25] chromatographic analysis, [26][27][28] molecular imprinting, 29 surface plasmon resonance, 30 eld-effect transistor sensors, 31 chemiluminescence, 32 and colorimetric methods 33,34 have been reported to detect cholesterol and H 2 O 2 . Among these methods, colorimetric detection is of great interest due to its simplicity, low cost, high sensitivity, and good selectivity.…”

Synthesis of Surface‐Modification‐Oriented Nanosized Molybdenum Disulfide with High Peroxidase‐Like Catalytic Activity for H2O2 and Cholesterol Detection

“…The ab-normalH 2 O 2 level in tissues can potentially induce various types of damage to cellular compartments, consequently causing aging, atherosclerosis, cancer,a nd renal diseases. Therefore, it is extremelye ssential to establish reliable methods to detectc holesterol with high sensitivitya nd selectivity.T od ate, various methods such as electrochemistry sensors, [6][7][8][9][10][11][12] fluorometric analysis, [13][14][15] chromatographic analysis, [16][17][18] molecular imprinting techniques, [19] surface plasma resonance, [20] fieldeffect-transistor sensors, [21] chemiluminescence, [22] and colorimetric methods [23,24] have been reported to detect cholesterol and H 2 O 2 .A mongt hem, the colorimetric methodi sp opular becauseo fi ts rapid ands imple operation as well as good reproducibility.I na ddition, the color change during colorimetric detection could be directly observed by the eyes insteado fb y using expensive instruments. [25,26] It is well known that natural horseradish peroxidase (HRP) can be used for colorimetricd etection.…”

“…Therefore, it is extremely essential to establish reliable methods to detect cholesterol with high sensitivity and selectivity. To date, various methods such as electrochemistry sensors, fluorometric analysis, chromatographic analysis, molecular imprinting techniques, surface plasma resonance, field‐effect‐transistor sensors, chemiluminescence, and colorimetric methods have been reported to detect cholesterol and H 2 O 2 . Among them, the colorimetric method is popular because of its rapid and simple operation as well as good reproducibility.…”