Modified phacoemulsification plus goniosynechialysis compared with conventional surgery for cataract and glaucoma

Tang, Yurong; Tan, Jianxin; Zhou, Xiaohong Joe; Li, Xiangji

doi:10.3892/etm.2019.8182

Cited by 5 publications

(5 citation statements)

References 21 publications

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“…Glaucoma is a major economic burden, with as many as 80 million patients by 2020 [17,53,54]. To our knowledge, this meta-analysis demonstrated, for the first time, a strong association between glaucoma and active H. pylori infection as documented by histology (Table 2) with total lack of heterogeneity.…”

Section: Discussionmentioning

confidence: 64%

“…Glaucoma, leads to the death of retinal ganglion cells and their axons and is the second most frequent cause of blindness worldwide. It affects 66.8 million individuals, causes bilateral blindness in 6.7 million people [ 15 , 16 , 17 ], and is a neurodegenerative disorder of the optic nerve, with the hallmark of increasing “cupping” of the optic disc [ 18 ].…”

Section: Introductionmentioning

confidence: 99%

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Association between Active Helicobacter pylori Infection and Glaucoma: A Systematic Review and Meta-Analysis

et al. 2020

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Background: Glaucoma is the second most common cause of blindness worldwide affecting almost 70 million individuals. Helicobacter pylori (H. pylori) is a widespread pathogen with systematic pathogenicity. This meta-analysis aimed to estimate the contradictory data regarding a potential association between active H. pylori infection and glaucoma. Materials and Methods: A research in MEDLINE/PubMed and Google Scholar was conducted and original studies investigating the relationship between H. pylori infection and glaucoma were included. Analysis was performed with random effects model. The main outcome was the odds ratio (OR) with 95% confidence intervals (CI) of H. pylori infection as a risk factor for glaucoma. A parallel analysis studied the role of active infection as indicated by histology and the titer of anti-H. pylori antibodies. For the anti-H. pylori antibody titers, weighted mean differences (WMD) were estimated between patients and controls. Results: Fifteen studies were included, with 2664 participants (872 patients with glaucoma and 1792 controls), divided into primary open-angle glaucoma (POAG), normal tension glaucoma (NTG) and pseudo-exfoliation glaucoma (PEG). The association between H. pylori infection and overall glaucoma was significant (OR = 2.08, CI 95% 1.48–2.93) with moderate heterogeneity (I2 = 61.54%). After stratification by glaucoma subtype, heterogeneity was eliminated in the NTG subgroup. Studies with healthy controls, and controls with anemia yielded very low or no heterogeneity, respectively. Gastric biopsy to document active H. pylori infection yielded the highest OR (5.4, CI: 3.17–9.2, p < 0.001) and null heterogeneity. For anti-H. pylori antibody titers, there was a significant difference in WMD between patients and controls (WMD 15.98 IU/mL; 95% CI: 4.09–27.87; p = 0.008); values were greater in glaucoma patients, with high heterogeneity (I2: 93.8%). Meta-regression analysis showed that mean age had a significant impact on glaucoma (p = 0.037). Conclusions: Active H. pylori infection may be associated with glaucoma with null heterogeneity, as, beyond histology, quantified by anti-H. pylori titers and increases with age.

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Section: Discussionmentioning

confidence: 64%

Section: Introductionmentioning

confidence: 99%

Association between Active Helicobacter pylori Infection and Glaucoma: A Systematic Review and Meta-Analysis

et al. 2020

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“…After phacoemulsification, we introduced viscoelastic into the anterior chamber to make the latter deeper, especially at the site of the anterior chamber angle. Tang and colleagues [12] used a technique for transection of synechia which is similar to ours. We used this technique for intraoperative gonioscopy and for effective GSL in the presence of synechiae.…”

Section: Discussionmentioning

confidence: 90%

Untitled

2020

Oftalmol Zh

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Background:To date, no universal surgical strategy exists for primary angle closure glaucoma (PACG). Purpose: To assess the clinical efficacy and hypotensive effect of phacoemulsification (phaco) combined with goniosynechialysis (GSL) for the treatment of PACG. Material and Methods: Nine patients (9 eyes; mean age, 63.4 ± 9.6 years) with chronic angle-closure glaucoma who were under our observation were included in this study. Of these, 8 (8 eyes) underwent phaco-GSL, and one (1 eye) underwent GSL at some time after phaco. Failure to control IOP (the IOP higher than 22 mmHg on maximal tolerable hypotensive therapy) and synechial closure of the anterior chamber angle was the indication for surgery. Results: Using the Mori goniolens was helpful in performing GSL in all anterior chamber quadrants.

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“…In this study, 12 articles that met the inclusion criteria were collected; we found that the modified phacoemulsification had better therapeutic effect and reduced the incidence rate of postoperative complications. In a study by Tang et al, compared with conventional surgery, the modified phacoemulsification (with lower ultrasound energy) and intraocular lens implantation was shown to better improve visual acuity and effectively reduce corneal edema and anterior chamber inflammation (25). Collectively, the modified phacoemulsification is safer and more effective.…”

Section: A B Cmentioning

confidence: 99%

Clinical efficacy of modified phacoemulsification in the treatment of high myopia with cataract: a systematic review and meta-analysis

Qi¹,

Yuan²,

Zhou³

et al. 2021

Ann Palliat Med

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Background: To use meta-analysis to evaluate the clinical effect of modified phacoemulsification in the treatment of high myopia with cataract. Methods:The English language databases of PubMed, Web of Science, and Embase, and Chinese language databases China National Knowledge Infrastructure (CNKI) and Wanfang were searched for relevant studies published from January 2010 to May 2021. The participants were divided into 2 groups according to different treatment methods; the control group mainly used traditional phacoemulsification, while the treatment group used modified phacoemulsification. The differences in the postoperative complication rate, visual acuity recovery rate at 1 month after surgery, and corneal endothelial cell count at 1 and 3 months after surgery were analyzed.Results: A total of 12 articles were included. The results of comparison confirmed that the treatment group was superior to the control group in the postoperative complication rate, visual acuity recovery rate at 1 month after surgery, and corneal endothelial cell count at 1 month and 3 months after surgery.Discussion: Both treatment methods are effective, but modified phacoemulsification has greater advantages in reducing the damage of corneal endothelial cells and postoperative complications and in improving patient prognosis. Additionally, modified phacoemulsification in the treatment of high myopia with cataract can achieve better visual acuity recovery than traditional phacoemulsification, suggesting a high value for clinical application.

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Modified phacoemulsification plus goniosynechialysis compared with conventional surgery for cataract and glaucoma

Cited by 5 publications

References 21 publications

Association between Active Helicobacter pylori Infection and Glaucoma: A Systematic Review and Meta-Analysis

Association between Active Helicobacter pylori Infection and Glaucoma: A Systematic Review and Meta-Analysis

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Clinical efficacy of modified phacoemulsification in the treatment of high myopia with cataract: a systematic review and meta-analysis

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