Modified Single Versus Double-Patch Technique for the Repair of Complete Atrioventricular Septal Defect

Yildirim, Ozgur; Avsar, M.; Özyüksel, Arda; Akdemir, Mehmet; Zeybek, Cenap; Demiroluk, Sener; Bilal, Mehmet Salih

doi:10.1111/jocs.12557

Cited by 12 publications

(7 citation statements)

References 21 publications

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“…Data from seven studies with 322 patients in the modified single-patch group and 275 in the two-patch group were pooled for the analysis of pacemaker implantation for atrioventricular block. 12,14 –19 An I 2 value of 0% demonstrated insignificant heterogeneity. There was no significant difference in the odds of postoperative pacemaker implantation for atrioventricular block between the two groups (odds ratio: 0.89, 95% confidence interval: 0.23-3.43).…”

Section: Resultsmentioning

confidence: 98%

“…A total of nine studies with 225 patients in the modified single-patch group and 332 in the two-patch group were pooled for the analysis of CPB time. 7,10 –18 An I 2 value of 70% demonstrated significant heterogeneity. The modified single-patch had a mean CPB time of 107 minutes and the two-patch repair had a mean time of 129 minutes.…”

Section: Resultsmentioning

confidence: 98%

“…Data from six studies with 149 patients in the modified single-patch group and 221 in the two-patch group were pooled for the analysis of total hospital length of stay. 10 –12,14,17,18 An I 2 value of 81% demonstrated significant heterogeneity. Mean total hospital length of stay for modified single-patch and two-patch repair was 11 days plus 7 hours and 12 days plus 9 hours, respectively.…”

Section: Resultsmentioning

confidence: 99%

“…Ten studies were finally included in the analysis (Figure 1). 7,10 –19 There were a total of 724 patients across these studies, with 353 (48.76%) having undergone modified single-patch repair and 371 (51.24%) having undergone two-patch repair for complete AVSD (Figure 1).…”

Section: Resultsmentioning

confidence: 99%

“…Data from eight studies with 334 patients in the modified single-patch group and 284 in the two-patch group were pooled for the analysis of need for reoperation for left ventricular outflow tract obstruction. 7,[12][13][14][15][16][17][18][19] An I 2 value of 67% demonstrated significant heterogeneity. There was no significant increase in the odds of need for reoperation for left ventricular outflow tract obstruction associated with modified single-patch repair (odds ratio: 0.31, 95% confidence interval: 0.01-6.98).…”

Section: Need For Reoperation For Left Ventricular Outflow Tract Obstmentioning

confidence: 99%

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Modified Single-Patch versus Two-Patch Repair for Atrioventricular Septal Defect: A Systematic Review and Meta-Analysis

Loomba

Flores

Villarreal

et al. 2019

World J Pediatr Congenit Heart Surg

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Background: We performed a meta-analysis of studies to determine whether the modified single-patch technique offers benefits when compared to the two-patch repair. The postoperative outcomes examined in this study were cardiopulmonary bypass time, cross-clamp time, duration of mechanical ventilation, intensive care unit length of stay, total hospital length of stay, need for reoperation, need for reoperation for left ventricular outflow tract obstruction or left atrioventricular valve regurgitation, need for pacemaker implantation, and mortality during follow-up. Methods: A review was conducted to identify studies comparing a modified single-patch repair versus two-patch repair. A fixed-effects model was utilized for end points with low heterogeneity and a random-effects model for end points with significant heterogeneity. Meta-regression was also performed to determine the influence of other factors on the variables of interest. Results: A total of 964 unique manuscripts were screened, with 10 being included in the final analyses. There were a total of 724 patients, with 353 (49%) having undergone repair utilizing a modified single-patch repair. Mean age at repair for modified single-patch repair and two-patch repair was 8.81 and 9.03 months, respectively. Significant differences were noted in cardiopulmonary bypass time and cross-clamp time with mean difference of −28.53 and −22.69 minutes, respectively. In comparison to the two-patch repair, both times were decreased in modified single-patch repair. No significant difference was noted in any other variables. Conclusions: Modified single-patch repair for atrioventricular septal defects requires less cardiopulmonary bypass and cross-clamp time but does not significantly impact the examined postoperative outcomes.

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Section: Resultsmentioning

confidence: 98%

Section: Resultsmentioning

confidence: 98%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Need For Reoperation For Left Ventricular Outflow Tract Obstmentioning

confidence: 99%

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Modified Single-Patch versus Two-Patch Repair for Atrioventricular Septal Defect: A Systematic Review and Meta-Analysis

Loomba

Flores

Villarreal

et al. 2019

World J Pediatr Congenit Heart Surg

View full text Add to dashboard Cite

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Modified Single-Patch Technique Versus Two-Patch Technique for the Repair of Complete Atrioventricular Septal Defect: A Meta-Analysis

Fan

Iwase

et al. 2017

Pediatr Cardiol

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Technical selection for surgical repair of complete atrioventricular septal defect (CAVSD) still remains controversial. This meta-analysis aimed to compare the modified single-patch (MP) technique with the two-patch (TP) technique for patients with CAVSD. Relevant studies comparing the MP technique with the TP technique were identified through a literature search using MEDLINE, EMBASE, Google Scholar, Cochrane Library, and the China National Knowledge Infrastructure databases. The variables were ventricular septal defect (VSD) size, cardiopulmonary bypass (CBP) time, aortic cross-clamp (ACC) time, intensive care unit stay, hospital stay, and other outcomes involving mortality, left ventricular outflow tract obstruction, atrioventricular valve regurgitation, residual septal shunt, atrioventricular block, and reoperation. A random-effect/fixed-effect model was used to summarize the estimates of mean difference/odds ratio with 95% confidence interval. Subgroup analysis stratified by region was performed. Fifteen publications involving 1034 patients were included. This meta-analysis demonstrated that (1) VSD size in the MP group was significantly smaller; (2) CBP time, ACC time, and hospital stay in the MP group experienced improvement; (3) Other postoperative outcomes showed no significant differences between two groups; and (4) The trends in China and other countries were close. The MP and TP techniques had comparable outcomes; however, the MP technique was performed with significantly shorter CBP and ACC times in patients with smaller VSDs. Given this limitation of data, the results of comparison of the two techniques in patients with larger VSDs remain unknown. Further studies are needed.

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Modified Single Repair Technique for Complete Atrioventricular Septal Defect: A Propensity Score Matching Analysis

Wang

Pang

et al. 2020

Pediatr Cardiol

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Modified Single Versus Double-Patch Technique for the Repair of Complete Atrioventricular Septal Defect

Cited by 12 publications

References 21 publications

Modified Single-Patch versus Two-Patch Repair for Atrioventricular Septal Defect: A Systematic Review and Meta-Analysis

Modified Single-Patch versus Two-Patch Repair for Atrioventricular Septal Defect: A Systematic Review and Meta-Analysis

Modified Single-Patch Technique Versus Two-Patch Technique for the Repair of Complete Atrioventricular Septal Defect: A Meta-Analysis

Modified Single Repair Technique for Complete Atrioventricular Septal Defect: A Propensity Score Matching Analysis

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