Modified Titanium Surface with Nano Amorphous Calcium Phosphate@Chitosan Oligolactate as Ion Loading Platform with Multifunctional Properties for Potential Biomedical Application

Pantović Pavlović, Marijana R.; Ignjatović, Nenad L.; Gudić, Senka; Vrsalović, Ladislav; Božić, Katarina Đ.; Popović, Marko E.; Pavlović, Miroslav M.

doi:10.1007/s10439-024-03521-0

Ann Biomed Eng

2024

DOI: 10.1007/s10439-024-03521-0

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Modified Titanium Surface with Nano Amorphous Calcium Phosphate@Chitosan Oligolactate as Ion Loading Platform with Multifunctional Properties for Potential Biomedical Application

Marijana R. Pantović Pavlović,

Nenad L. Ignjatović,

Senka Gudić

et al.

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2024

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Advanced titanium implants: combating corrosion and infection with cutting-edge coatings

Pantović Pavlović,

Ignjatović,

Gudić

et al. 2024

Corrosion Reviews

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The presented research investigates the corrosion behavior of commercially pure titanium (cp-Ti) and amorphous calcium phosphate–chitosan (ACP@ChOL) coatings enriched with selenium on titanium in simulated body fluid (SBF). Using potentiodynamic polarization techniques, it was sought to derive essential corrosion parameters – corrosion potential, corrosion current density, breakdown potential, and passivation current. This study pioneers a comparative analysis of the corrosion stability of both samples. SEM/EDS analysis of surfaces pre- and postpotentiodynamic measurements offered insights into morphology and elemental composition. The aim was to elucidate the corrosion mechanism by integrating these techniques. Additionally, spontaneous corrosion behavior over 7 days, monitoring changes in open circuit potential, polarization resistance, and impedance were investigated. Furthermore, the antimicrobial efficacy of ACP@ChOL enriched with Se on titanium was assessed against Escherichia coli, Staphylococcus aureus, and Candida albicans, as well as in vitro release of Se. The presented study extends understanding, offering a unique perspective on the corrosion behavior and antimicrobial attributes of ACP@ChOL coatings enriched with Se on titanium. This composite material exhibits promise for medical applications, presenting an innovative avenue for addressing corrosion concerns and potentially reducing antibiotic reliance.

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Advanced titanium implants: combating corrosion and infection with cutting-edge coatings

Pantović Pavlović,

Ignjatović,

Gudić

et al. 2024

Corrosion Reviews

View full text Add to dashboard Cite

show abstract

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Modified Titanium Surface with Nano Amorphous Calcium Phosphate@Chitosan Oligolactate as Ion Loading Platform with Multifunctional Properties for Potential Biomedical Application

Cited by 1 publication

References 69 publications

Advanced titanium implants: combating corrosion and infection with cutting-edge coatings

Advanced titanium implants: combating corrosion and infection with cutting-edge coatings

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