2017
DOI: 10.1093/bioinformatics/btx285
|View full text |Cite
|
Sign up to set email alerts
|

modlAMP: Python for antimicrobial peptides

Abstract: Supplementary data are available at Bioinformatics online.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1
1
1

Citation Types

0
142
0
3

Year Published

2018
2018
2020
2020

Publication Types

Select...
6
1

Relationship

2
5

Authors

Journals

citations
Cited by 146 publications
(157 citation statements)
references
References 31 publications
0
142
0
3
Order By: Relevance
“…org). [17] Theg enerationo fn ovel peptides from at emplate sequence was conducted by SME, as described. [9a] Them utation operatorw as based on physicochemical amino acid similarity.…”
Section: Methodsmentioning
confidence: 99%
“…org). [17] Theg enerationo fn ovel peptides from at emplate sequence was conducted by SME, as described. [9a] Them utation operatorw as based on physicochemical amino acid similarity.…”
Section: Methodsmentioning
confidence: 99%
“…54,55 However, some of the resulting peptides might also be toxic because some of the properties neglected for their design, such as hydrophobic-related features, lead to high affinity towards eukaryotic membranes. 56 Design strategies are now taking into consideration more complex descriptors, and the AMPs generated de novo are more selective for prokaryotic cells, 39,57,58 not only for antimicrobial purposes but for other biochemical processes, such as peptide substrates for enzymes 59 that affect essential biochemical pathways of prokaryotic microorganisms. The in silico exploration have allowed to expand the usefulness of peptides for other technological uses.…”
Section: Mutagenesismentioning
confidence: 99%
“…Daten im .txt-Format wurdenmittels Te xtWrangler (BareBones SoftwareInc., North Chelmsford,U SA) in das .csv-oder .xslx-Format konvertiert. [17] Die Generierung neuer Peptide aus der Elternsequenz erfolgte mittels SME. [14] Die Implementierung und Programmausführung wurde mittels Anaconda Software Distribution Tool (v [15] und seaborn (v.0.7.1) in Python durchgeführt.…”
Section: Experimentellesunclassified
“…[16] Der pep-CATS-Deskriptor wurde mithilfe des modlamp.descriptor-Moduls des modlAMP-Python-Pakets (v.3.4.0), http://www.modlamp.org) berechnet. [17] Die Generierung neuer Peptide aus der Elternsequenz erfolgte mittels SME. [9a, 10] Die Sequenzend er generiertenP eptide wurden im FASTA-Format gespeichert und mittels MolFromFasta aus RDKit (Verçffentlichung 2017.09.1, http://www.rdkit.org) in das .mol-Format und anschließend mit MolToSmiles in das SMILES-Format konvertiert.…”
Section: Peptidgruppeunclassified