2024
DOI: 10.1039/d4ob00564c
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Modular and divergent synthesis of 2,N3-disubstituted 4-quinazolinones facilitated by regioselective N-alkylation

Kelly E. Kim,
Jason R. Comber,
Alexander J. Pursel
et al.

Abstract: The synthesis of a biologically relevant 2-amino-N3-alkylamido 4-quinazolinone has been accomplished in four steps from commercially available materials using design principles from both modular and divergent synthesis. N3-alkylation of 2-chloro-4(3H)-quinazolinone...

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