We study the implications of 't Hooft anomaly (i.e. obstruction to gauging) on conformal field theory, focusing on the case when the global symmetry is Z 2 . Using the modular bootstrap, universal bounds on (1+1)-dimensional bosonic conformal field theories with an internal Z 2 global symmetry are derived. The bootstrap bounds depend dramatically on the 't Hooft anomaly. In particular, there is a universal upper bound on the lightest Z 2 odd operator if the symmetry is anomalous, but there is no bound if the symmetry is non-anomalous. In the non-anomalous case, we find that the lightest Z 2 odd state and the defect ground state cannot both be arbitrarily heavy. We also consider theories with a U (1) global symmetry, and comment that there is no bound on the lightest U (1) charged operator if the symmetry is non-anomalous.