Modular Functional Organization of Cat Anterior Auditory Field

Imaizumi, Kazuo; Priebe, Nicholas J.; Crum, Poppy; Bedenbaugh, Purvis; Cheung, Steven W.; Schreiner, Christoph E.

doi:10.1152/jn.01173.2003

Cited by 82 publications

(94 citation statements)

References 68 publications

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“…1, 8B). These extrinsic clusters of labeling were focal in each area and, in the tonotopic areas, aligned with CF maps (Imaizumi et al, 2004;Lee et al, 2004b). The major extrinsic input arose from AI (>30%), with other tonotopic fields each providing ~10-20%, and non-tonotopic regions contributing <5% each (Fig.…”

Section: Anterior Auditory Field (Aaf)supporting

confidence: 55%

Connections of cat auditory cortex: III. Corticocortical system

Lee

Winer

2008

J of Comparative Neurology

101

115

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The mammalian auditory cortex (AC) is essential for computing the source and decoding the information contained in sound. Knowledge of AC corticocortical connections is modest other than in the primary auditory regions, nor is there an anatomical framework in the cat for understanding the patterns of connections among the many auditory areas. To address this issue, we investigated cat AC connectivity in thirteen auditory regions. Retrograde tracers were injected in the same area or in different areas to reveal the areal and laminar sources of convergent input to each region. Architectonic borders were established in Nissl and SMI-32 immunostained material. We assessed the topography, convergence, and divergence of the labeling. Intrinsic input constituted >50% of the projection cells in each area, and extrinsic inputs were strongest from functionally related areas. Each area received significant convergent ipsilateral input from several fields (5 to 8; mean 6). These varied in their laminar origin and projection density. Major extrinsic projections were preferentially from areas of the same functional type (tonotopic to tonotopic, non-tonotopic to non-tonotopic, limbic-related to limbic-related, multisensory-to-multisensory), while smaller projections link areas belonging to different groups. Branched projections between areas were <2% with deposits of two tracers in an area or in different areas. All extrinsic projections to each area were highly and equally topographic and clustered. Intrinsic input arose from all layers except layer I, and extrinsic input had unique, area-specific infragranular and supragranular origins. The many areal and laminar sources of input may contribute to the complexity of physiological responses in AC and suggest that many projections of modest size converge within each area rather than a simpler area-to-area serial or hierarchical pattern of corticocortical connectivity.

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Section: Anterior Auditory Field (Aaf)supporting

confidence: 55%

Connections of cat auditory cortex: III. Corticocortical system

Lee

Winer

2008

J of Comparative Neurology

101

115

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“…It has been suggested that the AAF in the cat is homologous to the caudomedial (CM) belt area in the primate brain (see de la Mothe et al, 2006 for a discussion of the similarities between the primate CM and cat AAF). Like the primate CM (Recanzone, 2000), both the cat and ferret AAFs have shorter response latencies relative to the A1 and an under‐representation of mid‐frequencies (Imaizumi et al, 2004; Bizley et al, 2005). The AAF in the cat is innervated predominantly by the rostral pole of the MGB and the dorsal division of the MGB, with smaller inputs from the MGBv and MGBm (Imig and Morel, 1983; Morel and Imig, 1987; Lee and Winer, 2008a).…”

Section: Discussionmentioning

confidence: 99%

Cortico‐cortical connectivity within ferret auditory cortex

Bizley

Bajo

Nodal³

et al. 2015

J of Comparative Neurology

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Despite numerous studies of auditory cortical processing in the ferret (Mustela putorius), very little is known about the connections between the different regions of the auditory cortex that have been characterized cytoarchitectonically and physiologically. We examined the distribution of retrograde and anterograde labeling after injecting tracers into one or more regions of ferret auditory cortex. Injections of different tracers at frequency‐matched locations in the core areas, the primary auditory cortex (A1) and anterior auditory field (AAF), of the same animal revealed the presence of reciprocal connections with overlapping projections to and from discrete regions within the posterior pseudosylvian and suprasylvian fields (PPF and PSF), suggesting that these connections are frequency specific. In contrast, projections from the primary areas to the anterior dorsal field (ADF) on the anterior ectosylvian gyrus were scattered and non‐overlapping, consistent with the non‐tonotopic organization of this field. The relative strength of the projections originating in each of the primary fields differed, with A1 predominantly targeting the posterior bank fields PPF and PSF, which in turn project to the ventral posterior field, whereas AAF projects more heavily to the ADF, which then projects to the anteroventral field and the pseudosylvian sulcal cortex. These findings suggest that parallel anterior and posterior processing networks may exist, although the connections between different areas often overlap and interactions were present at all levels. J. Comp. Neurol. 523:2187–2210, 2015. © 2015 Wiley Periodicals, Inc.

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“…The auditory cortex of the cat comprises a number of fields that differ in their anatomical connections (Huang and Winer 2000;Lee and Winer, 2007;Morel and Imig 1987;Rouiller et al 1991) and physiological response properties (Imaizumi et al 2004;Lee et al 2004a, b;Irvine 1981, 1982;Reale and Imig 1980). Three of these fields-the primary (A1), anterior (AAF), and posterior (PAF) auditory fields-receive robust input from the ventral division of the medial geniculate body (MGB) (Morel and Imig 1987;Huang and Winer 2000).…”

Section: Introductionmentioning

confidence: 99%

Spatial sensitivity of neurons in the anterior, posterior, and primary fields of cat auditory cortex

et al. 2008

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We assessed the spatial-tuning properties of units in the cat's anterior auditory field (AAF) and compared them with those observed previously in the primary (A1) and posterior auditory fields (PAF). Multi-channel, silicon-substrate probes were used to record single-and multi-unit activity from the right hemispheres of α-chloralose-anesthetized cats. Spatial tuning was assessed using broadband noise bursts that varied in azimuth or elevation. Response latencies were slightly, though significantly shorter in AAF than A1, and considerably shorter in both of those fields than in PAF. Compared to PAF, spike counts and latencies were more poorly modulated by changes in stimulus location in AAF and A1, particularly at higher sound pressure levels. Moreover, units in AAF and A1 demonstrated poorer level tolerance than units in PAF with spike rates modulated as much by changes in stimulus intensity as changes in stimulus location. Finally, spike-pattern-recognition analyses indicated that units in AAF transmitted less spatial information, on average, than did units in PAF-an observation consistent with recent evidence that PAF is necessary for sound-localization behavior, whereas AAF is not.

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Modular Functional Organization of Cat Anterior Auditory Field

Cited by 82 publications

References 68 publications

Connections of cat auditory cortex: III. Corticocortical system

Connections of cat auditory cortex: III. Corticocortical system

Cortico‐cortical connectivity within ferret auditory cortex

Spatial sensitivity of neurons in the anterior, posterior, and primary fields of cat auditory cortex

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