Modular Platforms for Optofluidic Systems

Brammer, Marko; Mappes, Timo

doi:10.2478/optof-2013-0001

Cited by 2 publications

(1 citation statement)

References 89 publications

(36 reference statements)

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“…In micro-optofluidic devices, in order to deliver, as close as possible, the input light to the sample or a specific chip section and, collect the output signal, it is necessary to miniaturize optical components [3]. Integration of optical components in a single device allows a rapid investigation of biological and chemical samples [4][5][6][7].…”

Section: Introductionmentioning

confidence: 99%

Micro-Optical Waveguides Realization by Low-Cost Technologies

Cairone

Afflitto

Stella

et al. 2022

Micro

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Microscale optofluidic devices are a category of microscale devices combining fluidic and optical features. These devices typically enable in-situ fluid flow measurement for pharmaceutical, environmental or biomedical applications. In micro-optofluidic devices, in order to deliver, as close as possible, the input light to the sample or a specific chip section and, collect the output signal, it is necessary to miniaturize optical components. In this paper, two low-cost technologies, 3D Printing PDMS-based and laser cutting PMMA-based (PDMS stands for Poly-dimethyl-siloxane and PMMA for Poly-methyl-methacrylate), were investigated as novel methods to realize micro-optical waveguides (μWGs) comparing their performances. An ad-hoc master-slave protocol developed to realize PDMS components by 3D Printing has been fully optimized. The manufacturing technologies proposed require simple and low-cost equipment and no strictly controlled environment. Similar results are obtained for both the micro-optical waveguides realized. Their losses, disregarding the losses caused by the fibers’ alignment and the miss-match of the geometry with the waveguide, are of the order of 20%, almost equivalent for both approaches (PDMS-μWG and PMMA-μWG). The losses are of the order of 10% when the PDMS-μWG is shielded by a copper layer, with a significant improvement of the signal acquired. The results obtained show the possibility of using the two low-cost technologies presented for the realization of micro-optical waveguides suitable to be integrated in micro-optofluidic devices and the potential of creating micro-optical paths inside micro-embedded systems.

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Section: Introductionmentioning

confidence: 99%

Micro-Optical Waveguides Realization by Low-Cost Technologies

Cairone

Afflitto

Stella

et al. 2022

Micro

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Miniaturization of fluorescence sensing in optofluidic devices

Măriuța

Colin

Barrot-Lattes

et al. 2020

Microfluid Nanofluid

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Successful development of a micro-total-analysis system (µTAS, lab-on-a-chip) is strictly related to the degree of miniaturization, integration, autonomy, sensitivity, selectivity, and repeatability of its detector. Fluorescence sensing is an optical detection method used for a large variety of biological and chemical assays, and its full integration within lab-on-a-chip devices remains a challenge. Important achievements were reported during the last few years, including improvements of previously reported methodologies, as well as new integration strategies. However, a universal paradigm remains elusive. This review considers achievements in the field of fluorescence sensing miniaturization, starting from off-chip approaches, representing miniaturized versions of their lab counter-parts, continuing gradually with strategies that aim to fully integrate fluorescence detection on-chip, and reporting the results around integration strategies based on optical-fiber-based designs, optical layer integrated designs, CMOS-based fluorescence sensing, and organic electronics. Further successful development in this field would enable the implementation of sensing networks in specific environments that, when coupled to Internet-of-Things (IoT) and artificial intelligence (AI), could provide real-time data collection and, therefore, revolutionize fields like health, environmental, and industrial sensing.

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Modular Platforms for Optofluidic Systems

Cited by 2 publications

References 89 publications

Micro-Optical Waveguides Realization by Low-Cost Technologies

Micro-Optical Waveguides Realization by Low-Cost Technologies

Miniaturization of fluorescence sensing in optofluidic devices

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