Modulation Effect in Oncothermia

Szász, Olivér; Andócs, Gábor; Meggyesházi, Nóra

doi:10.1155/2013/398678

Cited by 14 publications

(15 citation statements)

References 24 publications

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“…Oncothermia is a capacitive impedance coupled energyabsorption, it heats the sensitive parts of the malignant cells selectively and effectively. The details of these effects were discussed in numerous papers and chapters of books [43,[46][47][48][49][50][51][52][53].…”

Section: Hyperthermia Heating Equipment and Techniquesmentioning

confidence: 99%

“…The Radiofrequency (RF) current is chosen with a proper amplitude modulated radiofrequency [71], which is absorbed by the nanoscopic range of the malignant cells (45). The physiological differences of the malignant cells from their healthy counterparts [68] distinguishes the malignancy which is self-selected by additional time-fractal modulation [72], and on such way it is also highly personalized [73].…”

Section: Hyperthermia Heating Equipment and Techniquesmentioning

confidence: 99%

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A Brief Overview of Hyperthermia in Cancer Treatment

Baronzio¹,

Parmar²,

Ballerini³

et al. 2014

J Integr Oncol

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Despite the large economic and intellectual efforts, cancer is still not easily treatable disease by conventional therapies. This led ultimately to reconsider hyperthermia, like one of interesting treatment methods connected to immunity and tumor metabolism. Hyperthermia has also the ability to play an additional role when used together with the conventional methods of treatment: surgery, radiotherapy, chemotherapy and immunotherapy. Recent trials in Holland and Germany have demonstrated that hyperthermia can prolong life and decrease disease re-appraisal when used in combination with radiotherapy and chemotherapy. Some tumors seem more responsive than others. In this brief summary we will attempt to give a vision of hyperthermia from a physical stand point, but more importantly we will give clinical and biological aspects. The results obtained in these trials on certain types of cancers such as cervix cancer, recurrent breast cancer and head neck cancer, melanoma, sarcomas, liver, glioblastoma and pancreatic cancer support the use of this technique, although some clinical and technical problems persist and have not been completely resolved.

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Section: Hyperthermia Heating Equipment and Techniquesmentioning

confidence: 99%

Section: Hyperthermia Heating Equipment and Techniquesmentioning

confidence: 99%

A Brief Overview of Hyperthermia in Cancer Treatment

Baronzio¹,

Parmar²,

Ballerini³

et al. 2014

J Integr Oncol

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“…This idea is applied in the modulated electro-hyperthermia treatment process, when the modulation mimics the healthy homeostatic noise [25].…”

Section: Connection Between the Fluctuation And The Induced Noise Theorymentioning

confidence: 99%

Intrinsic Noise Monitoring of Complex Systems

Szász¹,

Szigeti²,

Szász³

2017

OJBIPHY

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The power-density function of the noise spectrum of open and complex systems changes by the power of frequency. We show that the fluctuation origin and the noise-powered description are equivalent to describe the colored noise power density. Based on this, we introduce a scale-independent invariant for monitoring the dynamics of the complex system. The monitoring of the noise spectrum of the system specifies the forecast of failure, the timing of desired regular corrections and/or the assessed operation life of the system, indicating the possible faults before it happens, predicting deterioration like wear/tear, fatigue in the still properly working system. These considerations are highly applicable to living systems and their preventive care.

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“…The temperature from SAR in the stationary process can be derived from the non-linear Pennes equation [87]. Blood perfusion, metabolic heat and temperature dependence of the target leads to non-linearity.…”

Section: Appendix: Temperature On Membrane Raftsmentioning

confidence: 99%

Nanoheating without Artificial Nanoparticles

Vincze

Andócs

et al. 2015

Biol Med (Aligarh)

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Our aim is to describe the physical and physiological effects of local modulated electro-hyperthermia (mEHT). The method concentrates on the energy absorption of cluster rafts of the plasma membrane. The targeted cluster contains transmembrane proteins, which can form coherent working voltage-gated ion channels and/or TRP receptors in one domain. This targeting is analogous to nanoparticle heating, except this uses readily available nanoparticles on the cell membrane instead of the artificially placed nano-object to induce selective energy absorption from the outside field. In the discussed non-artificial nanoparticle heating, selectivity is the consequence of the synergy of various interactions embedded into each other in their effective volume in macro-, micro-and nano-ranges.

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Modulation Effect in Oncothermia

Cited by 14 publications

References 24 publications

A Brief Overview of Hyperthermia in Cancer Treatment

A Brief Overview of Hyperthermia in Cancer Treatment

Intrinsic Noise Monitoring of Complex Systems

Nanoheating without Artificial Nanoparticles

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