2018
DOI: 10.1007/s12094-018-1947-8
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Modulation of cancer cells’ radiation response in the presence of folate conjugated Au@Fe2O3 nanocomplex as a targeted radiosensitizer

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Cited by 18 publications
(9 citation statements)
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“…It neutralizes the superoxide anion free radical, thereby reducing damage to cells by oxygen free radicals. The antioxidant capacity of body tissues can be evaluated clinically by determining SOD activity [16].…”
Section: Discussionmentioning
confidence: 99%
“…It neutralizes the superoxide anion free radical, thereby reducing damage to cells by oxygen free radicals. The antioxidant capacity of body tissues can be evaluated clinically by determining SOD activity [16].…”
Section: Discussionmentioning
confidence: 99%
“…GNPs conjugated with targeting moieties also exhibit excellent radiosensitization effects that culminate in apoptosis induction. For example, folate-conjugated Au@Fe 2 O 3 NPs (44 nm) exhibited radiosensitization effects in KB cells by elevating the apoptosis rate [141]. EGFR antibody-decorated hollow gold nanospheres (anti-EGFR/HGNs, 55 nm) induced the downregulation of Bcl-2 and the upregulation of caspase 3, Bax, and Bad in HeLa cells under irradiation [121].…”
Section: Nanoradiosensitizers Based On Apoptosismentioning
confidence: 99%
“…As this part of nanotechnology application is still newfound, there are not enough convincing evidences to ensure health-care authorities around the world for any mid-or long-term effects of these newborn particles on human organs. To minimize any unwanted effects, specialist's recommendation would clearly be "does enhancement" [1][2][3]. Dose enhancement of local or systematic application of nanoparticles has attracted a great deal of attention as expected.…”
Section: Introductionmentioning
confidence: 99%