Modulation of NRF2 and CYP24A1 Pathways by Hookah Smoke: Implications for Male Reproductive Health
Amir Masoud Firouzabadi,
Maryam Imani,
Maryam Tofighi Niaki
et al.
Abstract:Antioxidants act by preventing excessive oxidative stress within the developing sperm cells. Hookah smoking has been implicated in inducing oxidative stress which may be a risk factor for male infertility. This study aims to bridge this knowledge gap by evaluating the effect of hookah smoking on sperm quality and the expression of nuclear factor erythroid 2-related factor 2 ( NRF2) and Cytochrome P450 family 24 subfamily A member 1 ( CYP24A1) genes which are involved in antioxidant response. Young fertile men … Show more
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