Modulation of Immunity and Barrier Function in Pre- And Postnatal Animal Ontogenesis. Mechanisms of Natural Resistance in Newborn Piglets

Abstract

Non-specific protection of the animal body are represented by various proteins and peptides 1 . They are present in the various biological fluids and circulate in the blood of animals in the significant amount to maintain the homeostasis 2 . These factors have antimicrobial properties or have the ability to activate other humoral and cellular immune defense mechanisms 3 .Immunoglobulins, namely antibodies, are the group of soluble glycoproteins that persist in peripheral blood and biological fluids 4 . They have the ability to interact with antigens and thus cause neutralization of the latter 56 . This specific recognizing is accompanied by the antigen-antibody immune complex formation, which circulate in the blood for a while 7 .