Modulation of NFκB Signaling during Intermittent Hypoxia by Nitric Oxide.

Jf, Garvey; Ryan, S.J.; McNicholas, WT; Taylor, CT

doi:10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a1069

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Autonomic Nervous System: Sympathetic Nervous System1

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2014

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“…The role of NO has been described in patients with essential hypertension showing a determinant for the premature development of atherosclerosis (17) . Further, several studies have reported the influence of NO on stimulating soluble guanylyl cyclase activity in vascular smooth muscle cells (18) impairing BP and cellular events such as renal hemodynamics, vasodilation, leukocyte adhesion and cellular proliferation and thrombosis (19,20) . Besides, ET-1 is also considered to be an important factor in the development of vascular dysfunction and cardiovascular complications beyond pulmonary arterial hypertension (21) .…”

Section: Autonomic Nervous System: Sympathetic Nervous Systemmentioning

confidence: 99%