Modulation of the Migrating Myoelectric Complexes by Cholecystokinin and Gastrin in the Gastrointestinal Tract of Chickens

Martı́nez, Vicente; Jiménez, Marcel; Goñalons, E.; Vergara, Patri

doi:10.3382/ps.0740563

Cited by 9 publications

(8 citation statements)

References 22 publications

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“…Contraction of chicken ileal strips is stimulated by CCK-8 acting predominantly via receptors on neurons . Administration of CCK influences the migrating myoelectric complexes that control intestinal motility in the chicken intestine in a manner similar to that of feeding (Martínez et al, 1995). Sulfated CCK-8 induces hyperactivity in the duodenum (Martinez et al, 1993b).…”

Section: Cholecystokinin (Cck)mentioning

confidence: 97%

Biology of the Gastrointestinal Tract in Poultry

Scanes

Pierzchała-Koziec

2014

Avian Biology Research

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This review provides an overview of the anatomy and physiology of the gastro-intestinal tract (GIT) of poultry, particularly of the domesticated chicken. The structure and functioning of the major regions of the GIT are discussed bringing together recent studies with the older, often neglected, literature. Attention is focused on the GIT as an immune organ and on GIT fermentation/bacterial colonisation. In addition, the interactions of nutrition with GIT biology are discussed. The roles of neuropeptides and hormones on the development and functioning of the GIT are extensively reviewed.

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Section: Cholecystokinin (Cck)mentioning

confidence: 97%

Biology of the Gastrointestinal Tract in Poultry

Scanes

Pierzchała-Koziec

2014

Avian Biology Research

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“…The detailed mechanisms of regulation of the MMC in chickens have not been reported yet, but it is known that the appearance of the MMC is modulated by some gut hormones such as CCK and gastrin. The difference in the motility of the GI tract in fed and fasted states is unclear at present in the case of the bird MMC (70, 71).…”

Section: Regulation Of Gastrointestinal Motility By Mlnmentioning

confidence: 99%

“…The morphology and function of the GI tract in birds are different from those in mammals in the following three aspects: (i) the crop in the middle of the esophagus stocks food, (ii) there are two distinct stomach structures, the proventriculus that secretes digestive enzymes for chemical digestion and the gizzard for mechanical digestion, and (iii) a pair of a long cecum and short colon/rectum. Electromyogram measurements showed that the MMC, consisting of three phases like the mammalian IMC, is also present in the GI tract of avian species including chickens ( Gallus gallus domesticus ) (70, 71). However, the MMC originates from the duodenum, not the stomach, and it appears in both fed and fasted states, being different from the mammalian IMC.…”

Section: Regulation Of Gastrointestinal Motility By Mlnmentioning

confidence: 99%

Regulation of Gastrointestinal Motility by Motilin and Ghrelin in Vertebrates

Kitazawa

Kaiya

2019

Front. Endocrinol.

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The energy balance of vertebrates is regulated by the difference in energy input and energy expenditure. Generally, most vertebrates obtain their energy from nutrients of foods through the gastrointestinal (GI) tract. Therefore, food intake and following food digestion, including motility of the GI tract, secretion and absorption, are crucial physiological events for energy homeostasis. GI motility changes depending on feeding, and GI motility is divided into fasting (interdigestive) and postprandial (digestive) contraction patterns. GI motility is controlled by contractility of smooth muscles of the GI tract, extrinsic and intrinsic neurons (motor and sensory) and some hormones. In mammals, ghrelin (GHRL) and motilin (MLN) stimulate appetite and GI motility and contribute to the regulation of energy homeostasis. GHRL and MLN are produced in the mucosal layer of the stomach and upper small intestine, respectively. GHRL is a multifunctional peptide and is involved in glucose metabolism, endocrine/exocrine functions and cardiovascular and reproductive functions, in addition to feeding and GI motility in mammals. On the other hand, the action of MLN is restricted and species such as rodentia, including mice and rats, lack MLN peptide and its receptor. From a phylogenetic point of view, GHRL and its receptor GHS-R1a have been identified in various vertebrates, and their structural features and various physiological functions have been revealed. On the other hand, MLN or MLN-like peptide (MLN-LP) and its receptors have been found only in some fish, birds and mammals. Here, we review the actions of GHRL and MLN with a focus on contractility of the GI tract of species from fish to mammals.

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“…For example, intravenous injection of CCK suppresses food intake in chickens (Savory and Gentle, 1980). CCK also modulates intestinal motility (Martín et al, 1995;Martínez et al, 1995;Rodríguez-Sinovas et al, 1997) and biliary flow in the gallbladder of chickens (Duke et al, 1987). Furthermore, CCK stimulates amylase secretion from the pancreas in chickens and ducks (Satoh et al, 1994;Xiao and Cui, 2004).…”

Section: Introductionmentioning

confidence: 99%

Effect of a Single-Nucleotide Polymorphism in the <i>Cholecystokinin Type A Receptor</i> Gene on Growth Traits in the Hinai-dori Chicken Breed

et al. 2013

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We have previously reported the association between chicken cholecystokinin type A receptor gene (CCKAR) haplotypes and growth traits in an F 2 resource population produced by crossing low-and high-growth lines of the Hinai-dori breed. The high-growth line was developed from a low-growth founder from the Preservation Society of the Hinai-dori breed by long-term selection for growth performance at the Akita Prefectural Livestock Experiment Station. In the present study, we determined the effect of a single-nucleotide polymorphism (SNP, AB604331: g.420 C＞A) in the 5′ -untranslated region of CCKAR on the growth traits of the F 2 population. A mismatch amplification mutation polymerase chain reaction assay was developed to distinguish between the 3 genotypes (A/A, A/C, and C/C) in the F 2 population, and the effect of the SNP on growth traits was estimated. The data showed that body weight at 10 and 14 weeks of age, and average daily gain between 4 and 10 weeks, 10 and 14 weeks, and 0 and 14 weeks of age in individuals with the A allele was superior to that in those with the C allele. The electrophoretic mobility shift assay was performed to clarify the contribution of the g. 420 C＞A SNP in the predicted YY1 binding site. As a result, the YY1 protein showed a stronger binding affinity for g.420 A probe, suggesting the possibility that the SNP affects transcriptional efficiency of the CCKAR. The A allele frequencies in the high-and low-growth lines maintained in fiscal year 2010 were 0.889 and 0.124, respectively. The difference in the allele frequencies of these lines is thought to be caused by long-term selection for growth performance since the probability was too significantly (P＜0.01) low to be caused by random genetic drift.

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Modulation of the Migrating Myoelectric Complexes by Cholecystokinin and Gastrin in the Gastrointestinal Tract of Chickens

Cited by 9 publications

References 22 publications

Biology of the Gastrointestinal Tract in Poultry

Biology of the Gastrointestinal Tract in Poultry

Regulation of Gastrointestinal Motility by Motilin and Ghrelin in Vertebrates

Effect of a Single-Nucleotide Polymorphism in the <i>Cholecystokinin Type A Receptor</i> Gene on Growth Traits in the Hinai-dori Chicken Breed

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